COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults (Dyn3CEA_Nosocor)

NCT04664296 | Completed

• 1 other identifier: 69HCL20_1100
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Unlike other respiratory viruses such as influenza and Respiratory Syncytial Virus (RSV) where the child is the essential reservoir and central vector of intrafamilial contamination, the child is likely to be a small player in the transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SRAS-CoV2) infection. This study aims to describe the age category of the first contact, within 14 days before the appearance of the first symptoms of the index case in order to describe the age categories of this first contaminant, globally, in the group of children and finally in the group of adults. This work is intended to provide food for discussion and to justify the distancing and containment measures imposed on children when their isolation has a deleterious impact that has now been established for some children.

Conditions

Infection Viral

Outcome Measures

Primary Outcomes (1)

• Percentage of possible contaminants, adults, adolescents and children with Covid-19

  To describe the age category of the 1st possible contaminant in the index case to show the preponderance of possible adult and adolescent contaminants in the SARS-Cov-2 contamination. Percentage of possible contaminants, adults, adolescents and children, in matched children and adults with Covid-19.

  at inclusion

Study Arms (2)

Children

Hospitalized children, 0 to 17 years of age, 25 subjects, consecutive sample survey

Other: Review of medical patient file

Adults

Hospitalized adults, 18 years and above, 50 matched subjects

Other: Phone call interview

Interventions

Review of medical patient file OTHER

Review of medical patient file, including patient tracing, brief summary of the disease course, barrier gestures, social distancing.

Children

Phone call interview OTHER

less than 15 minutes phone call

Adults

Eligibility Criteria

• Age: 0 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Hospital-based population of children and adults: * Hospitalized children, 0 to 17 years of age, 25 subjects, consecutive sample survey * Hospitalized adults, 18 years and above, 50 matched subjects

You may qualify if:

• Children after hospitalized in Hospices Civils de Lyon with Polymerase Chain Reaction (PCR) positive SARS-CoV2,
• Adults hospitalized in Hospices Civils de Lyon and included in the NOSO-COR study with matching criteria described below.
• Matching will be performed on family age characteristics and on the period of contamination included in the containment period to minimize bias, and if possible frequency matching according to admission in Intensive Care Unit ICU/Pediatric Intensive Care Unit (PICU), and to family structure (n of children / n of adults in the family).

You may not qualify if:

• Any patient suspected of nosocomial infection.
• Any patient death during the Covid-19 infection.
• Any adult patient without children living home.
• Opposition to participate.

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Service de Reanimation Pediatrique

Lyon, Rhone, 69003, France

Location

MeSH Terms

Conditions

Virus Diseases

Condition Hierarchy (Ancestors)

Infections

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 10, 2020
• First Posted: December 11, 2020
• Study Start: December 21, 2020
• Primary Completion: March 23, 2021
• Study Completion: March 23, 2021
• Last Updated: April 26, 2021

Record last verified: 2021-04

Locations

FR (1)