EFFECT OF COVID-19 DISEASE IN SMELL AND TASTE OF PATIENTS WITH MILD, MODERATE OR SEVERE SYMPTOMATOLOGY

NCT04657445 | Completed

• 1 other identifier: 931/17-11-2020
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This is an observational data and recording study. The aim of our study is to investigate the effect of SARS-COV2 infection on patients' sense of smell and taste, through quality control measurements using optic analogue scale (VAS) in hospitalized and in home-quarantined patients.

Conditions

Olfactory and Taste Dysfunction in SARS-CoV2 Infection

Keywords

Olfactory, taste dysfunction, SARS-CoV2, COVID-19

Outcome Measures

Primary Outcomes (1)

• oflactory and taste dysfunction in SARS-CoV2 infection

  4 WEEKS

Study Arms (2)

home-quarantined patients

home-quarantined patients

Diagnostic Test: visual analogue scale

inhospitalized patients

inhospitalized patients

Diagnostic Test: visual analogue scale

Interventions

visual analogue scale DIAGNOSTIC_TEST

A visual analog scale (VAS) is a measurement device used to quantify a subjective experience.

home-quarantined patients; inhospitalized patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will be divided in two groups. The first group will be consisted with positive patients that were referred to either the Emergency Department (ED) of Infectious Diseases or at the Outpatient Clinic screening for SARS-COV2 and are being self-quarantined at home. The participants of the second group will be hospitalized patients in the Infectious Diseases Unit (IDU) of the University General Hospital of Ioannina.

You may qualify if:

• adult\>18 years old
• COVID-19 positive patient, via RT-PCR test
• Patient referred to the University General Hospital of Ioannina

You may not qualify if:

• Age \<18
• Previous nasal surgery, endoscopic sinus surgery
• Head and neck radiotherapy
• Head injury
• Allergic rhinitis
• Chronis Rhinosinusitis
• Psychiatric/ Neurological disorders
• Disorders that altering the level of consciousness (Glasgow Coma Scale \<15)
• History of smell and taste disorder

Sponsors & Collaborators

• University Hospital, Ioannina: lead

Study Sites (1)

University General Hospital of Ioannina

Ioannina, Epirus, 45500, Greece

Location

MeSH Terms

Conditions

Anosmia; Taste Disorders; COVID-19

Interventions

Pain Measurement

Condition Hierarchy (Ancestors)

Olfaction Disorders; Sensation Disorders; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Neurologic Examination; Physical Examination; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• CHARALAMPOS MILIONIS, PROFESSOR

  University Hospital, Ioannina

  PRINCIPAL INVESTIGATOR

• IOANNIS KASTANIOUDAKIS, PROFESSOR

  University Hospital, Ioannina

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: CONSULTANT OF INTERNAL MEDICINE

Study Record Dates

• First Submitted: December 6, 2020
• First Posted: December 8, 2020
• Study Start: November 17, 2020
• Primary Completion: May 31, 2021
• Study Completion: June 30, 2021
• Last Updated: September 13, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

GR (1)