NCT05548998|Completed
Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly
Effect of Low Fresh Gas Flow Volatile Anesthetics on Postoperative Neurocognitive Function in Elderly Patients
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Effect of Low Fresh Gas Flow Volatile Anesthetics on Postoperative Neurocognitive Function in Elderly Patients
Sponsor study identifier
observational
230
1 country
1
Study Start
May 1, 2019
Actual (reported)Primary Completion
November 1, 2019
Actual (reported)Study Completion
November 1, 2019
Actual (reported)This study aims to investigate the effect of inhaled anesthetics with a low fresh gas flow on cognitive function of elderly patients undergoing elective surgery
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 1, 2019
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 1, 2019
Actual (reported)November 1, 2019
Actual (reported)November 1, 2019
Actual (reported)September 17, 2022
Actual (reported)September 22, 2022
Actual (reported)Change from baseline in neurocognitive status on the 30 point MMSE at postoperative 24th hour
A Mini-Mental State Examination (MMSE) is a set of 11 questions that doctors and other healthcare professionals commonly use to check for cognitive impairment (problems with thinking, communication, understanding and memory).
Baseline and postoperative day 1
Change from baseline in neurocognitive status on the 30 point MMSE at postoperative 6th hour
Baseline and postoperative hour 6
Change from baseline in neurocognitive status on the 30 point MMSE at postoperative 3rd day
Baseline and postoperative day 3
Change from baseline in neurocognitive status on the 30 point MMSE at postoperative 7th day
Baseline and postoperative day 7
Change from baseline in pain on the 10 point VAS scale at postoperative 6th hour
Baseline and postoperative hour 6
Change from baseline in pain on the 10 point VAS scale at postoperative 24th hour
Baseline and postoperative hour 24
Patients, whose maintenance phase of anesthesia is managed with a fresh gas flow ≥ 1L/min, were included in this cohort.
Patients, whose maintenance phase of anesthesia is managed with a fresh gas flow \< 1L/min, were included in this cohort.
General anesthesia with a fresh gas flow lower than 1L/min for the maintenance phase of anesthesia
General anesthesia with a fresh gas flow equal to or higher than 1L/min for the maintenance phase of anesthesia
Cohorts were selected from geriatric patients (\>65 y.o.) of a tertiary care clinic who underwent surgery under general anesthesia with different fresh gas flows for the maintenance phase.
Prof. Dr. Cemil Taşcıoğlu City Hospital
Istanbul, 34384, Turkey (Türkiye)
Namigar TURGUT
Prof. Dr. Cemil Taşcıoğlu City Hospital
230 participants (actual enrollment reported by the registry).
First Submitted
September 17, 2022
First Posted
September 22, 2022
Study Start
May 1, 2019
Actual (reported)Effects of Episodic Specificity Induction in Normal and Pathological Ageing.
6 category and 30-point test to inquire patient's cognitive function
The patient's self-reported pain intensity according to a visual scale between 0 and 100
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
November 1, 2019
Actual (reported)Study Completion
November 1, 2019
Actual (reported)Last Updated
September 22, 2022
Record last verified: 2022-09
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Source: ClinicalTrials.gov.
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