Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB

NCT04654663 | Completed

• 1 other identifier: 4-2020-1128
• Study Type: observational
• Target: 605
• Locations: 1 country
• Sites: 1

Brief Summary

Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.

Conditions

Coronary Artery Occlusive Disease

Outcome Measures

Primary Outcomes (3)

• postoperative pulmonary complications : pneumonia

  CXR with at least one of the following: infiltrate, consolidation, cavitation;plus at least one of the following: fever \>38 °C with no other cause, white cell count \<4 or\>12\*109 litre-1, \>70 yr of age with altered mental status with no other cause;-plus at least two of the following: new purulent/ changed sputum, increased secretions/suctioning, new/worse cough/dyspnoea/tachypnoea, rales/ bronchial breath sounds, worsening gas exchange.

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative pulmonary complications : prolonged ventilation

  Indicate whether the patient had prolonged post-operative pulmonary ventilation \> 24.0 hours. The hours of postoperative ventilation time include OR exit until extubation, plus any additional hours following reintubation.

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative pulmonary complications : reintubation

  Indicate whether the patient was intubated for the first time after leaving the OR from the initial procedure, or re-intubated during the hospital stay after the initial extubation.

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

Secondary Outcomes (6)

• postoperative complications : Renal failure

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative complications : Delirium

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative complications : Reoperation due to bleeding/tamponade

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative complications : Permanent stroke

  During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.

• postoperative complications : Mortality

  During the hospitalization in which the operation was performed, even if after 30 days.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who undersent off-pump coronary artery bypass graft surgery.

You may qualify if:

• Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery)
• serum cystatin C and creatinine test results were valid within one week before surgery

You may not qualify if:

• Patients with chronic renal failure (estimated glomerular filtration rate less than 60)
• Patients with acute kidney injury
• Patients with respiratory tract infection within 1 month before surgery

Sponsors & Collaborators

• Yonsei University: lead

Study Sites (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine

Seoul, South Korea

Location

Study Officials

• Young-Lan Kwak, MD, PhD

  Severance Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 29, 2020
• First Posted: December 4, 2020
• Study Start: December 7, 2020
• Primary Completion: January 15, 2021
• Study Completion: January 15, 2021
• Last Updated: July 28, 2021

Record last verified: 2021-07

Locations

KR (1)