The Mechanical Properties of Burned Muscles

NCT04654572 | Completed

• 1 other identifier: 2018-05
• Study Type: interventional
• Target: 37
• Locations: 1 country
• Sites: 1

Brief Summary

The investigate of mechanical properties of muscles in burned patients.

Conditions

Burns; Muscle Loss; Viscoelastic Properties; Stiffness

Keywords

Burn; muscle; myotonometer; viscoelasticity; stiffness

Outcome Measures

Primary Outcomes (3)

• Stiffness

  Myotonometric measurement was used to determine for muscle stiffness. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

  6 week

• Elasticity

  Myotonometric measurement was used to determine for muscle elasticity. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

  6 week

• Tone

  Myotonometric measurement was used to determine for muscle tone. Device has a probe that creates constant pre-excitations and generates short-term, low-force mechanical stimulations over skin. The stimulations induce damped natural oscillations in the tissue and the myoton device records these oscillations with an accelerometer. Muscle tone, elasticity, and stiffness are calculated separately by the device.

  6 week

Study Arms (2)

burned group

EXPERIMENTAL

burned patients

Diagnostic Test: Myotonometric measurement

control group

EXPERIMENTAL

sedentary people

Diagnostic Test: Myotonometric measurement

Interventions

Myotonometric measurement DIAGNOSTIC_TEST

Myotonometric assessment can predict the muscle stiffness, tone and elasticity

burned group; control group

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• burned patient
• major burn over %20 TBSA

You may not qualify if:

• Amputation
• Dead
• Systemic disease and abuse

Sponsors & Collaborators

• Hasan Kalyoncu University: lead

Study Sites (1)

Hasan kalyoncu üniversity

Gaziantep, 27144, Turkey (Türkiye)

Location

Related Publications (3)

• Gittings PM, Grisbrook TL, Edgar DW, Wood FM, Wand BM, O'Connell NE. Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis. Burns. 2018 Jun;44(4):731-751. doi: 10.1016/j.burns.2017.08.009. Epub 2017 Oct 7.

  PMID: 29017743 BACKGROUND

• Porter C, Hardee JP, Herndon DN, Suman OE. The role of exercise in the rehabilitation of patients with severe burns. Exerc Sport Sci Rev. 2015 Jan;43(1):34-40. doi: 10.1249/JES.0000000000000029.

  PMID: 25390300 BACKGROUND

• Ianieri G, Saggini R, Marvulli R, Tondi G, Aprile A, Ranieri M, Benedetto G, Altini S, Lancioni GE, Goffredo L, Bellomo RG, Megna M, Megna G. New approach in the assessment of the tone, elasticity and the muscular resistance: nominal scales vs MYOTON. Int J Immunopathol Pharmacol. 2009 Jul-Sep;22(3 Suppl):21-4. doi: 10.1177/03946320090220S304. No abstract available.

  PMID: 19887038 BACKGROUND

MeSH Terms

Conditions

Burns; Muscular Atrophy

Condition Hierarchy (Ancestors)

Wounds and Injuries; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: SCREENING
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant of professeur

Study Record Dates

• First Submitted: November 27, 2020
• First Posted: December 4, 2020
• Study Start: June 6, 2018
• Primary Completion: March 20, 2019
• Study Completion: August 20, 2020
• Last Updated: December 16, 2020

Record last verified: 2020-12

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, CSR
• Time Frame: after publication and 10 years

Locations

TU (1)