Comparison of the Effects of Static and PNF Hamstring Stretching Exercises in Patients With Knee Osteoarthritis

NCT04645238 | Completed

• 1 other identifier: DEU-FTR-IK-01
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to determine and compare the effects of static and PNF hamstring stretching exercises on joint pain, hamstring flexibility and functional status in patients with knee osteoarthritis.

Conditions

Knee Osteoarthritis

Keywords

Knee Osteoarthritis; Hamstring; Stretching

Outcome Measures

Primary Outcomes (2)

• Active Knee Extension Test for Hamstring Flexibility

  Higher values represent better outcomes.

  Baseline and post-intervention

• Active Knee Extension Test for Hamstring Flexibility

  Higher values represent better outcomes.

  Post-intervention and follow-up

Secondary Outcomes (6)

• Visual Analogue Scale for Pain

  Baseline and post-intervention

• Visual Analogue Scale for Pain

  Post-intervention and follow-up

• Western Ontario and McMaster Universities Osteoarthritis Index

  Baseline and post-intervention

• Western Ontario and McMaster Universities Osteoarthritis Index

  Post-intervention and follow-up

• The Timed Up & Go Test

  Baseline and post-intervention

Study Arms (2)

Static Hamstring Stretching

ACTIVE COMPARATOR

Static Hamstring Stretching

Other: Static Stretching

PNF Stretching

ACTIVE COMPARATOR

PNF Hamstring Stretching (Hold-Relax)

Other: PNF Stretching

Interventions

Static Stretching OTHER

Static hamstring stretching exercise lasting 30 seconds and 10 repetitions under the supervision of the physiotherapist

Static Hamstring Stretching

PNF Stretching OTHER

PNF hold-relax stretching technique that consists of 10 seconds isometric contraction, 30 seconds hamstring stretching and 10 repetitions under the supervision of the physiotherapist

PNF Stretching

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals with knee osteoarthritis severity II, III, or IV according to the Kellgren-Lawrence Classification,
• Individuals with positive active knee extension test,
• Individuals with a body mass index of 30 or less,
• Individuals with a pain severity of at least 3/10 according to the visual pain scale.

You may not qualify if:

• Individuals with health problems that prevent them from doing the evaluations and exercises to be used in the study,
• Individuals who exercise regularly for the last six months,
• Individuals with a diagnosis of neurological disease affecting the lower extremity.

Sponsors & Collaborators

• Dokuz Eylul University: lead

Study Sites (1)

Fizyotem Medical Center

Trabzon, Turkey (Türkiye)

Location

Related Publications (12)

• Reid DA, McNair PJ. Effects of an acute hamstring stretch in people with and without osteoarthritis of the knee. Physiotherapy. 2010 Mar;96(1):14-21. doi: 10.1016/j.physio.2009.06.010. Epub 2009 Sep 4.

  PMID: 20113758 BACKGROUND

• Hortobagyi T, Westerkamp L, Beam S, Moody J, Garry J, Holbert D, DeVita P. Altered hamstring-quadriceps muscle balance in patients with knee osteoarthritis. Clin Biomech (Bristol). 2005 Jan;20(1):97-104. doi: 10.1016/j.clinbiomech.2004.08.004.

  PMID: 15567543 BACKGROUND

• Krishnasamy P, Hall M, Robbins SR. The role of skeletal muscle in the pathophysiology and management of knee osteoarthritis. Rheumatology (Oxford). 2018 May 1;57(suppl_4):iv22-iv33. doi: 10.1093/rheumatology/kex515.

  PMID: 29351644 BACKGROUND

• Rutherford DJ, Hubley-Kozey CL, Stanish WD. Changes in knee joint muscle activation patterns during walking associated with increased structural severity in knee osteoarthritis. J Electromyogr Kinesiol. 2013 Jun;23(3):704-11. doi: 10.1016/j.jelekin.2013.01.003. Epub 2013 Jan 26.

  PMID: 23357547 BACKGROUND

• Lempke L, Wilkinson R, Murray C, Stanek J. The Effectiveness of PNF Versus Static Stretching on Increasing Hip-Flexion Range of Motion. J Sport Rehabil. 2018 May 1;27(3):289-294. doi: 10.1123/jsr.2016-0098. Epub 2018 May 22.

  PMID: 28182516 BACKGROUND

• Lim KI, Nam HC, Jung KS. Effects on hamstring muscle extensibility, muscle activity, and balance of different stretching techniques. J Phys Ther Sci. 2014 Feb;26(2):209-13. doi: 10.1589/jpts.26.209. Epub 2014 Feb 28.

  PMID: 24648633 BACKGROUND

• Hill KJ, Robinson KP, Cuchna JW, Hoch MC. Immediate Effects of Proprioceptive Neuromuscular Facilitation Stretching Programs Compared With Passive Stretching Programs for Hamstring Flexibility: A Critically Appraised Topic. J Sport Rehabil. 2017 Nov;26(6):567-572. doi: 10.1123/jsr.2016-0003. Epub 2016 Aug 24.

  PMID: 27632820 BACKGROUND

• Maddigan ME, Peach AA, Behm DG. A comparison of assisted and unassisted proprioceptive neuromuscular facilitation techniques and static stretching. J Strength Cond Res. 2012 May;26(5):1238-44. doi: 10.1519/JSC.0b013e3182510611.

  PMID: 22395273 BACKGROUND

• Fasen JM, O'Connor AM, Schwartz SL, Watson JO, Plastaras CT, Garvan CW, Bulcao C, Johnson SC, Akuthota V. A randomized controlled trial of hamstring stretching: comparison of four techniques. J Strength Cond Res. 2009 Mar;23(2):660-7. doi: 10.1519/JSC.0b013e318198fbd1.

  PMID: 19204565 BACKGROUND

• Yildirim MS, Ozyurek S, Tosun O, Uzer S, Gelecek N. Comparison of effects of static, proprioceptive neuromuscular facilitation and Mulligan stretching on hip flexion range of motion: a randomized controlled trial. Biol Sport. 2016 Mar;33(1):89-94. doi: 10.5604/20831862.1194126. Epub 2016 Feb 8.

  PMID: 26929476 BACKGROUND

• Alghadir AH, Anwer S, Iqbal A, Iqbal ZA. Test-retest reliability, validity, and minimum detectable change of visual analog, numerical rating, and verbal rating scales for measurement of osteoarthritic knee pain. J Pain Res. 2018 Apr 26;11:851-856. doi: 10.2147/JPR.S158847. eCollection 2018.

  PMID: 29731662 BACKGROUND

• Song Q, Shen P, Mao M, Sun W, Zhang C, Li L. Proprioceptive neuromuscular facilitation improves pain and descending mechanics among elderly with knee osteoarthritis. Scand J Med Sci Sports. 2020 Sep;30(9):1655-1663. doi: 10.1111/sms.13709. Epub 2020 Jun 1.

  PMID: 32407583 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Muscle Stretching Exercises

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Nihal Gelecek, Professor

  Dokuz Eylul University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: November 20, 2020
• First Posted: November 27, 2020
• Study Start: September 1, 2019
• Primary Completion: September 30, 2020
• Study Completion: September 30, 2020
• Last Updated: April 9, 2025

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)