NCT04642872

Brief Summary

mCIMT and BIT are therapies applied in children with hemiplegia which have a great evidence, but not in a early age. This research has the objective to know the effects of this therapies in infants diagnosed of infantile hemiplegia from 9 to 18 months applying 50 hours of dose for both interventions during 10 weeks, executing them at home by familes.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 28, 2019

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

November 3, 2020

Completed
21 days until next milestone

First Posted

Study publicly available on registry

November 24, 2020

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 18, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 20, 2021

Completed
Last Updated

November 24, 2020

Status Verified

November 1, 2020

Enrollment Period

1.5 years

First QC Date

November 3, 2020

Last Update Submit

November 22, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • mini Assisting Hand Assesment

    Bimanual functional performance Assessment in children with hemiplegia from 8 to 18 months.

    10 weeks

Secondary Outcomes (1)

  • Satisfaction questionnaire for familes

    10 weeks

Study Arms (4)

infant cimt

EXPERIMENTAL
Other: Infant BITOther: Infant CIMT/BITOther: Conventional therapy

Infant BIT

ACTIVE COMPARATOR
Other: Infant CIMT/BITOther: Conventional therapyOther: infant cimt

Infant CIMT/BIT

ACTIVE COMPARATOR
Other: Infant BITOther: Conventional therapyOther: infant cimt

Conventional Therapy

ACTIVE COMPARATOR
Other: Infant BITOther: Infant CIMT/BITOther: infant cimt

Interventions

Not use of unaffected hand containment. Both hand are use to improve the bimanual coordination

Conventional TherapyInfant CIMT/BITinfant cimt

Use unaffected hand containment in part of the intervention and then, both hands in bimanual activities without containment.

Conventional TherapyInfant BITinfant cimt

Following the usual therapy in the baby.

Infant BITInfant CIMT/BITinfant cimt

use of unaffected hand containment to improve the use of affected hand with unimanual activities

Conventional TherapyInfant BITInfant CIMT/BIT

Eligibility Criteria

Age9 Months - 18 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Infantile hemiplegia
  • Age from 9 months to 18 months.
  • No use of the affected upper limb

You may not qualify if:

  • Associated pathologies
  • Epilepsy no controlled with medicins
  • No collaborated families

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hemiweb

Barcelona, Spain

RECRUITING

Related Publications (1)

  • Palomo-Carrion R, Pinero-Pinto E, Romay-Barrero H, Escobio-Prieto I, Lillo-Navarro C, Romero-Galisteo RP. Shall we start? Ready, set, go! Toward early intervention in infants with unilateral cerebral palsy. A randomized clinical trial protocol. Ther Adv Chronic Dis. 2022 Nov 14;13:20406223221136059. doi: 10.1177/20406223221136059. eCollection 2022.

MeSH Terms

Conditions

HemiplegiaParesis

Condition Hierarchy (Ancestors)

ParalysisNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Rocío Palomo Carrión

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

November 3, 2020

First Posted

November 24, 2020

Study Start

July 28, 2019

Primary Completion

January 18, 2021

Study Completion

March 20, 2021

Last Updated

November 24, 2020

Record last verified: 2020-11

Data Sharing

IPD Sharing
Will not share

Locations