Objective Visual Acuity Measurement Using Suppression of the Optokinetic Nystagmus (OKN).

NCT04642495 | Completed

• 1 other identifier: 2016-02078
• Study Type: observational
• Target: 246
• Locations: 1 country
• Sites: 1

Brief Summary

Suppression of the optokinetic nystagmus when a target is perceived can be applied to assess visual acuity objectively. Our aim is to establish prediction intervals for this optokinetic nystagmus suppression test (Speedwheel Test, SW) so that SW acuity may be used to estimate Snellen acuity (FrACT- C and -E) in the clinic in adults and children unable to cooperate in other acuity testing.

Conditions

Visual Acuity

Outcome Measures

Primary Outcomes (1)

• Prediction intervals of Snellen acuity for the SW

  Prediction intervals of Snellen acuity for the SW compared to Landolt C and E symbols

  12 months

Secondary Outcomes (1)

• Prediction intervals of Snellen acuity for Landolt C compared to E symbols

  12 months

Study Arms (1)

Human subjects aged 4 and above

Human volunteers aged 4 and above.

Diagnostic Test: Visual acuity testing with SW , Landolt-"C" and Tumbling-"E" symbols

Interventions

Visual acuity testing with SW , Landolt-"C" and Tumbling-"E" symbols DIAGNOSTIC_TEST

Establish prediction intervals for acuity tests

Human subjects aged 4 and above

Eligibility Criteria

• Age: 4 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

healthy volunteers aged 4 and above

You may qualify if:

• able and willing to perform the test

You may not qualify if:

• under 4 years of age
• unable or unwilling

Sponsors & Collaborators

• University of Basel: lead

Study Sites (1)

University Basel, University Eye Hospital Basel

Basel, 4031, Switzerland

Location

Related Publications (3)

• Schwob N, Palmowski-Wolfe A. Objective measurement of visual acuity by optokinetic nystagmus suppression in children and adult patients. J AAPOS. 2019 Oct;23(5):272.e1-272.e6. doi: 10.1016/j.jaapos.2019.05.016. Epub 2019 Sep 14.

  PMID: 31526857 BACKGROUND

• Schwob N, Palmowski-Wolfe A. Establishing an Objective Measurement of Visual Acuity with a Computerised Optokinetic Nystagmus Suppression Test. Klin Monbl Augenheilkd. 2020 Apr;237(4):502-505. doi: 10.1055/a-1119-6123. Epub 2020 Apr 24.

  PMID: 32330979 BACKGROUND

• Luethy ML, Schotzau A, Palmowski-Wolfe A. Establishing Prediction Intervals for the SpeedWheel Acuity Test in Adults and Children. Klin Monbl Augenheilkd. 2021 Apr;238(4):488-492. doi: 10.1055/a-1403-2218. Epub 2021 Apr 14.

  PMID: 33853189 RESULT

Study Officials

• Anja M Palmowski-Wolfe, Prof

  University Basel, University Eye Hospital Basel

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor Dr. med.

Study Record Dates

• First Submitted: November 17, 2020
• First Posted: November 24, 2020
• Study Start: October 1, 2019
• Primary Completion: July 30, 2020
• Study Completion: September 30, 2020
• Last Updated: May 10, 2021

Record last verified: 2021-05

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)