NCT04640753

Brief Summary

There will be a retrospective chart review for patients who underwent endoscopic procedures and POEM from 06/2016 - 01/2019 \& a prospective chart review will be performed for patients who will undergo endoscopic procedures and POEM from 02/2019 - 06/2021

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
6mo left

Started Feb 2019

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress94%
Feb 2019Feb 2027

Study Start

First participant enrolled

February 6, 2019

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

November 27, 2019

Completed
12 months until next milestone

First Posted

Study publicly available on registry

November 23, 2020

Completed
6.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 5, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 5, 2027

Last Updated

June 10, 2026

Status Verified

June 1, 2026

Enrollment Period

8 years

First QC Date

November 27, 2019

Last Update Submit

June 8, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Decrease or no symptoms of chest pain

    To continue and review our treatment outcomes, patient safety in cases with achalasia, we follow up after the procedure up to 180 days. Follow-up period varies from patient to patient.

    upto 180 days

Interventions

POEM procedure will have a high technical feasibility, with effective clinical resolution of symptoms both in the short and long term.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

There will be a retrospective chart review for patients who underwent endoscopic procedures and POEM from 06/2016 - 01/2019. In addition; a prospective chart review will be performed for patients who will undergo endoscopic procedures and POEM from 02/2019 - 06/2021.

You may qualify if:

  • Any discharged patient who has undergone clinically indicated and/or standard of care POEM for the treatment of Achalasia from 6/2016 to 6/2021.
  • Above or equal to 18 years of age

You may not qualify if:

  • Any patient who has not undergone POEM for the treatment of Achalasia.
  • Below 18 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Methodist Dallas Medical Center

Dallas, Texas, 75203, United States

RECRUITING

MeSH Terms

Conditions

Esophageal Achalasia

Interventions

Endoscopy

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, SurgicalDiagnostic Techniques and ProceduresDiagnosisMinimally Invasive Surgical ProceduresSurgical Procedures, Operative

Study Officials

  • Prashant Kedia, M.D.

    The Methodist Hospital Research Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Crystee Cooper, DHEd

CONTACT

Jennifer Kirchner

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 27, 2019

First Posted

November 23, 2020

Study Start

February 6, 2019

Primary Completion (Estimated)

February 5, 2027

Study Completion (Estimated)

February 5, 2027

Last Updated

June 10, 2026

Record last verified: 2026-06

Locations