Neuroprotective Effects of Lidocaine on Early Postoperative Cognitive Dysfunction in Patients Undergoing Shoulder Arthroscopy With Beach Chair Position: a Randomized Trial
Sponsor study identifier
interventional
80
1 country
1
Study Start
January 7, 2021
Actual (reported)Primary Completion
November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
The beach chair position (BCP) combined with deliberate hypotension impair cerebral perfusion pressure and oxygenation during arthroscopic shoulder surgeries and produce cerebral ischemia.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
November 12, 2020
Actual (reported)November 18, 2020
Actual (reported)January 7, 2021
Actual (reported)November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Postoperative cognitive function
Assessed using Mini-Mental State Examination (MMSE) test
3 days after surgery
Patients will receive lidocaine in a loading dose of 1 mg/ kg diluted in 10 ml of normal saline that will be infused over 5 minutes after induction of anesthesia then followed by a continuous infusion at 1.5 mg/ kg/ h diluted in normal saline to a volume of 50 ml until the end of surgery.
Patients will receive normal saline after induction of anesthesia with the same volume and rate changes as lidocaine group until the end of surgery.
Patients will receive lidocaine in a loading dose of 1 mg/ kg diluted in 10 ml of normal saline that will be infused over 5 minutes after induction of anesthesia then followed by a continuous infusion at 1.5 mg/ kg/ h diluted in normal saline to a volume of 50 ml until the end of surgery
Patients will receive normal saline after induction of anesthesia with the same volume and rate changes as lidocaine group until the end of surgery
Seham Mohamed Moeen
Asyut, Asyut Governorate, 71515, Egypt
Seham M Moeen, MD
Assiut University
First Submitted
November 12, 2020
First Posted
November 18, 2020
Study Start
January 7, 2021
Actual (reported)Primary Completion
November 10, 2021
Estimated (date passed)Ketamine and Changes of the Short Portable Mental Status Questionnaire
Serum Opiorphin Level After Intraoperative Intravenous Lidocaine Infusion
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This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 10, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
January 8, 2021
Record last verified: 2021-01
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