Posterior Narrow Diameter Implants in Hyperglycemic and Normo-glycemic Patients
Evaluation of Posterior Narrow Diameter Implants in Hyperglycemic and Normo-glycemic Patients
1 other identifier
observational
35
0 countries
N/A
Brief Summary
The aim of the present study was to compare the initial healing and long term performance of narrow diameter implants in patients with uncontrolled Diabetes mellitus type 2 (T2DM) and healthy individuals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2012
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2017
CompletedFirst Submitted
Initial submission to the registry
November 13, 2020
CompletedFirst Posted
Study publicly available on registry
November 16, 2020
CompletedNovember 16, 2020
November 1, 2020
4 years
November 13, 2020
November 13, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
No difference
3 months
Study Arms (2)
Control
Patients with HbA1c around 6,0
T2DM
Patients with HbA1c above 6,5
Interventions
Patients received narrow diameter implants in posterior mandible or maxilla
Eligibility Criteria
All
You may qualify if:
- Patients with one or more missing teeth posterior to the canine either in the maxilla or mandible and associated with diminished alveolar ridge dimensions were included in the study
You may not qualify if:
- immobility of diabetic patients
- periodontal surgery and/or antibiotic therapy within the last 6 months prior to baseline
- pregnancy and lactation period
- Full Mouth Plaque Score (FMPS) \> 25%
- untreated periodontitis
- smoking \> 10 cigarettes/day
- insufficient crestal volume making an augmentation procedure necessary
- previously performed ridge augmentation procedure for a staged implant placement
- permanent medication potentially affecting blood perfusion rate and bone metabolism
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Witten/Herdeckelead
- Institut Straumann AGcollaborator
Related Publications (3)
Diehl D, Bespalov A, Yildiz MS, Friedmann A. Restoration of posterior teeth by narrow diameter implants in hyperglycemic and normoglycemic patients - 4-year results of a case-control study. Clin Oral Investig. 2024 Jun 22;28(7):392. doi: 10.1007/s00784-024-05786-0.
PMID: 38907052DERIVEDDiehl D, Kaner D, Bockholt A, Bilhan H, Friedmann A. Microcirculation and neutrophil-related cytokine concentrations are not altered around narrow diameter implants in T2DM patients during wound healing. Clin Oral Investig. 2023 Mar;27(3):1167-1175. doi: 10.1007/s00784-022-04731-3. Epub 2022 Oct 13.
PMID: 36229741DERIVEDFriedmann A, Winkler M, Diehl D, Yildiz MS, Bilhan H. One-year performance of posterior narrow diameter implants in hyperglycemic and normo-glycemic patients-a pilot study. Clin Oral Investig. 2021 Dec;25(12):6707-6715. doi: 10.1007/s00784-021-03957-x. Epub 2021 May 3.
PMID: 33939006DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 13, 2020
First Posted
November 16, 2020
Study Start
December 1, 2012
Primary Completion
December 1, 2016
Study Completion
December 1, 2017
Last Updated
November 16, 2020
Record last verified: 2020-11
Data Sharing
- IPD Sharing
- Will not share