NCT04627714

Brief Summary

Literature have shown the benefit of practicing regular physical activity during and after cancer treatment, particularly in terms of improving quality of life. The French Fencing Federation has thus developed an adapted physical activity program (Solution RIPOSTE) specially intended for patients with breast cancer. Adapted fencing sessions (saber) are thus offered to these patients in a perfectly secure context (i.e. compulsory medical-sports evaluation and trained fencing master). Since 2016, this RIPOSTE program has been implemented in several fencing halls in Lorraine. Our research project (controlled, randomized trial) aims to assess the impact of the practice of adapted fencing on the quality of life of patients, the functional capacities of the operated side (shoulder) and on the reduction of the sides effects of treatments. Our hypothesis is that such an adapted fencing program improves quality of life as well as functional abilities.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2021

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 1, 2020

Completed
12 days until next milestone

First Posted

Study publicly available on registry

November 13, 2020

Completed
12 months until next milestone

Study Start

First participant enrolled

November 10, 2021

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2022

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

January 27, 2022

Status Verified

January 1, 2022

Enrollment Period

7 months

First QC Date

November 1, 2020

Last Update Submit

January 26, 2022

Conditions

Keywords

BreastNeoplamsadapted physical activity

Outcome Measures

Primary Outcomes (1)

  • Change from baseline score of Quality of Life Questionnaire Core 30 (QLQ-C30) at 3 months.

    Questionnaire. 30 items. minimum value = 30. Maximum value = 120. A high score means a worse outcome (i.e. poor quality of life)

    Baseline (J0) and at 3 months (M3)

Secondary Outcomes (3)

  • Change from baseline score of Disabilities of the Arm, Shoulder and Hand measurement tool (DASH) at 3 months

    Baseline (J0) and at 3 months (M3)

  • Change from baseline score of Multidimensional Fatigue Inventory (MFI-20) at 3 months

    Baseline (J0) and at 3 months (M3)

  • Change from baseline score of Hospital Anxiety and Depression Scale at 3 months.

    Baseline (J0) and at 3 months (M3)

Study Arms (2)

Early Fencing

EXPERIMENTAL

patients of the "Early Fencing" arm will start adapted fencing practice (1h30/week) within 4 weeks after the breast surgery and for a duration of 3 months

Other: Adapted Physical Activity

Delayed Fencing

EXPERIMENTAL

patients of the "Delayed Fencing" arm will start adapted fencing practice (1h30/week) 3 months after the breast surgery and for a duration of 3 months

Other: Adapted Physical Activity

Interventions

Intervention consists in 1h30/week of adapted fencing

Delayed FencingEarly Fencing

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be a woman
  • ≥ 18 years old.
  • Have undergone unilateral breast surgery for primary invasive breast cancer
  • Accept and be able to complete self-administered questionnaires
  • Satisfy the prior medico-sports evaluation
  • Be affiliated to a social security scheme or beneficiary of such a scheme
  • Have received full information on the organization of the research and have signed their informed consent.

You may not qualify if:

  • Presence of bone metastases, especially vertebral
  • Presence of a contraindication to the practice of fencing during the medico-sports evaluation (post-surgery period that is too painful and / or requiring specific treatment in rehabilitation)
  • Refusal to participate in the study
  • Woman of childbearing age who does not have effective contraception.
  • Persons referred to Articles L.1121-5, L.1121-7 and L. 1121-8 of the Public Health Code
  • Pregnant woman, parturient or nursing mother
  • Minor (non-emancipated)
  • Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
  • Person of full age unable to express consent
  • Persons deprived of their liberty by a judicial or administrative decision, persons undergoing psychiatric treatment under Articles L. 3212-1 and L. 3213-1.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Hia Legouest

Metz, France

RECRUITING

CHRU Nancy

Nancy, 54000, France

RECRUITING

Institut de Cancerologie de Lorraine

Vandœuvre-lès-Nancy, 54520, France

RECRUITING

Related Publications (1)

  • Omorou AY, Peiffert D, Rotonda C, Van Hoye A, Allado E, Hily O, Temperelli M, Chenuel B, Hornus-Dragne D, Poussel M. Adapted Fencing for Patients With Invasive Breast Cancer: The RIPOSTE Pilot Randomized Controlled Trial. Front Sports Act Living. 2022 Mar 29;4:786852. doi: 10.3389/fspor.2022.786852. eCollection 2022.

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Mathias POUSSEL, MD, PhD

    CHRU Nancy

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mathias POUSSEL, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

November 1, 2020

First Posted

November 13, 2020

Study Start

November 10, 2021

Primary Completion

June 1, 2022

Study Completion

November 1, 2022

Last Updated

January 27, 2022

Record last verified: 2022-01

Data Sharing

IPD Sharing
Will not share

Locations