Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome

NCT04613063 | Completed

• 1 other identifier: I1568Z
• Study Type: observational
• Target: 1
• Locations: 1 country
• Sites: 1

Brief Summary

A case of a patient with cystic fibrosis with bowel obstruction due to a proximal intestinal obstruction syndrome (PIOS) is presented.This syndrome can be diagnosed with the DIOS definition, with the only distinction of a more proximal location in the gastrointestinal tract, such as the stomach, the duodenum, or the jejunum.

Conditions

Cystic Fibrosis; Bowel Obstruction; Distal Intestinal Obstruction Syndrome

Outcome Measures

Primary Outcomes (1)

• Bowel obstruction in a patient with cystic fibrosis

  A 45 year old patient with cystic fibrosis presented with bowel obstruction. Image studies were performed, without identifying a specific cause of the bowel obstruction. The patient was transferred to surgery.

  3-6 days

Interventions

Diagnostic laparoscopy OTHER

A diagnostic laparoscopy was performed where a dilated jejunum was encountered with impaction of fecal content. Surgery was converted to open surgery, where a longitudinal enterotomy of 5 cm after the transition zone was created, evacuating manually the fecal material with mucous secretion.

Eligibility Criteria

• Sex: male
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

45 years old patient with cystic fibrosis

You may qualify if:

• Adult \>18 years
• Cystic fibrosis
• Bowel obstruction

You may not qualify if:

• Pediatric patient \<18 years
• Unknown cause of bowel obstruction

Sponsors & Collaborators

• Tecnologico de Monterrey: lead

Study Sites (1)

Escuela Nacional de Medicina, Tecnologico de Monterrey

Monterrey, Nuevo León, 76140, Mexico

Location

MeSH Terms

Conditions

Cystic Fibrosis; Intestinal Obstruction

Interventions

Laparoscopy

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases; Lung Diseases; Respiratory Tract Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Infant, Newborn, Diseases; Intestinal Diseases; Gastrointestinal Diseases

Intervention Hierarchy (Ancestors)

Endoscopy; Diagnostic Techniques, Surgical; Diagnostic Techniques and Procedures; Diagnosis; Minimally Invasive Surgical Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 21, 2020
• First Posted: November 3, 2020
• Study Start: October 19, 2020
• Primary Completion: October 20, 2020
• Study Completion: October 21, 2020
• Last Updated: November 3, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share

Locations

ME (1)