Cystic Fibrosis
1,360
81
119
938
Key Insights
Highlights
Success Rate
90% trial completion (above average)
Published Results
294 trials with published results (22%)
Research Maturity
938 completed trials (69% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
8.0%
109 terminated out of 1360 trials
89.6%
+3.0% vs benchmark
16%
220 trials in Phase 3/4
31%
294 of 938 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 938 completed trials
Clinical Trials (1360)
Trikafta in Cystic Fibrosis Patients
Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del
Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis
Streamlined Treatment of Pulmonary Exacerbations in Pediatrics
Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis
Impact of Telerehabilitation Training on Pediatric Cystic Fibrosis Patients: An Exploratory Study
Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis
HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy
Natural History of Noncirrhotic Portal Hypertension
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
Role of Genetic Factors in the Development of Lung Disease
Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants
A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa
Natural History of Bronchiectasis
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
High Resolution Micro OCT Imaging
Osteopathic Treatment in Adult Patients With Cystic Fibrosis
Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis