Key Insights

Highlights

Success Rate

90% trial completion (above average)

Published Results

292 trials with published results (21%)

Research Maturity

931 completed trials (68% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

7.9%

107 terminated out of 1360 trials

Success Rate

89.7%

+3.2% vs benchmark

Late-Stage Pipeline

16%

221 trials in Phase 3/4

Results Transparency

31%

292 of 931 completed with results

Key Signals

292 with results90% success107 terminated

Data Visualizations

Phase Distribution

951Total
Not Applicable (367)
Early P 1 (12)
P 1 (171)
P 2 (180)
P 3 (143)
P 4 (78)

Trial Status

Completed931
Unknown140
Terminated107
Recruiting84
Withdrawn39
Active Not Recruiting37

Trial Success Rate

89.7%

Benchmark: 86.5%

Based on 931 completed trials

Clinical Trials (1360)

Showing 20 of 20 trials
NCT04624490Phase 1Recruiting

Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease

NCT05444257Phase 3Active Not RecruitingPrimary

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

NCT06159725Phase 1Completed

A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis

NCT03921060Phase 4RecruitingPrimary

Markers of Osteoporosis in Cystic Fibrosis

NCT06371261Active Not RecruitingPrimary

Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis

NCT06322446Not ApplicableActive Not RecruitingPrimary

Exercise in People With Cystic Fibrosis on CFTR Modulator Therapy

NCT03435939Early Phase 1CompletedPrimary

Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240

NCT02417740RecruitingPrimary

Natural History of Noncirrhotic Portal Hypertension

NCT05844449Phase 3Enrolling By InvitationPrimary

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

NCT03655249Not ApplicableWithdrawnPrimary

Effects of AD on VI in Patients With CF

NCT06311292Not ApplicableCompletedPrimary

Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

NCT02918409Phase 4CompletedPrimary

IV Colistin for Pulmonary Exacerbations: Improving Safety and Efficacy

NCT04613128CompletedPrimary

The PROMISE Pediatric Study 6 to 11 Years Old

NCT00001532RecruitingPrimary

Role of Genetic Factors in the Development of Lung Disease

NCT00368446CompletedPrimary

Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease

NCT06147414Recruiting

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

NCT02700243Not ApplicableCompletedPrimary

Increase Tolerance for Exercise and Raise Activity Through Connectedness Trial

NCT04469439Recruiting

Impact of Sinus Surgery on Individuals With Cystic Fibrosis

NCT06413368Phase 2Recruiting

Maralixibat in Patients With Cystic Fibrosis and Constipation

NCT02323100Phase 1TerminatedPrimary

Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)

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