Ischemic Strokes While on NOAC - How Compliance Matters

NCT04607070 | Completed

• 1 other identifier: Crec 2020.427
• Study Type: observational
• Target: 91
• Locations: 1 country
• Sites: 1

Brief Summary

This study is aimed to depict the epidemiological trend, aetiologies, clinical characteristics, treatment options of IS-NOAC in face of the rapidly increasing NOAC usage. Knowledge on this ischaemic stroke entity will define clinical characteristics, identify preventable causes and inform resource allocation on the evaluation modalities, reperfusion strategies and forecast future burden of IS-NOAC.

Conditions

Stroke, Acute; Stroke Syndrome; Stroke, Cardiovascular; Atherosclerosis; Stroke, Ischemic; Ischemic Stroke

Keywords

stroke, NOAC

Outcome Measures

Primary Outcomes (1)

• Compliance affects the outcomes of ischemic stroke during NOAC usage.

  To depict epidemiological trend and aetiologies on different dosage of NOAC in stroke patients.

  30 Sept 2021

Study Arms (1)

Stroke patient

This is a registry-based study that will involve consecutive adult patients with known AF who developed ischaemic stroke or TIA in years 2010, 2012, 2014, 2016 and 2018.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with known AF who developed ischaemic stroke or TIA and admitted in the Prince of Wales Hospital in years 2010, 2012, 2014, 2016 and 2018 will be recruited into this study

You may qualify if:

• Patients who were ethnic Chinese
• Patients with known AF
• Patient who suffered from ischaemic stroke

You may not qualify if:

• Patient who are non-ethnic Chinese
• Patient who suffered from haemorrhagic stroke

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

Chinese University of Hong Kong

Hong Kong, Hong Kong

Location

MeSH Terms

Conditions

Ischemic Stroke; Stroke; Myocardial Infarction; Atherosclerosis

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Myocardial Ischemia; Heart Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis; Arteriosclerosis; Arterial Occlusive Diseases

Study Officials

• Yiu Ming Bonaventure IP, MBChB, MRCP

  Chinese University of Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist resident

Study Record Dates

• First Submitted: October 23, 2020
• First Posted: October 28, 2020
• Study Start: October 1, 2020
• Primary Completion: June 30, 2025
• Study Completion: June 30, 2025
• Last Updated: February 24, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)