Evaluation of the Root Resorption and Dehiscence Formation Between Two Methods of Leveling and Alignment of Lower Teeth

NCT04601662 | Completed DMC

• 1 other identifier: UDDS-Ortho-06-2020
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

The duration of orthodontic treatment is one of the exacerbation causes of orthodontic pain. Several methods have been suggested to reduce the duration of orthodontic treatment classified to surgical and non-surgical methods. Researchers used minimally invasive surgical methods like corticision, piezocision, micro-osteoperforation, and piezopuncture indicated that most of these methods can accelerate dental movement by 20 - 40%. The effect of corticision as a minimally invasive procedure on root resorption and dehiscence formation during orthodontic tooth movement has not been studied yet. Applying corticision on the lower anterior teeth using a surgical blade and a hammer may accelerate tooth alignment during orthodontic treatment. This study consists of two groups, patients will be randomly assigned to one of these two groups.

Conditions

Crowding of Anterior Mandibular Teeth

Outcome Measures

Primary Outcomes (1)

• Change in Root Length

  Cone-beam computed tomography imaging will be used for the lower jaw. Root length will be measured for each root of the six lower anterior teeth The change will be calculated between 'before' and 'after' images in mm.

  T1: one day before the beginning of the orthodontic treatment, T2: exactly at 12 months following the onset of orthodontic treatment

Secondary Outcomes (1)

• Change in Dehiscence Proportion

  T1: one day before the beginning of the orthodontic treatment, T2: exactly at 12 months following the onset of orthodontic treatment

Study Arms (2)

Corticision

EXPERIMENTAL

Patients in this group will be subjected to corticision to accelerate orthodontic movement

Procedure: Corticision

Traditional treatment

ACTIVE COMPARATOR

Patients in this group will undergo normal traditional treatment without any acceleration method.

Other: Traditional Non-accelerated Treatment

Interventions

Corticision PROCEDURE

A special instrument will be used to cut the cortex of the alveolar bone at different locations between the lower anterior teeth

Corticision

Traditional Non-accelerated Treatment OTHER

The normal sequence of treatment steps will be followed in this group without using any kind of acceleration methods

Traditional treatment

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age range between 18 and 24 years
• Completion permanent dentition (except third molars)
• Mild to moderate crowding (2-6 mm according to Little's index)
• Absence of medications intake that interferes with pain perception for at least one week before the beginning of the treatment

You may not qualify if:

• Medical conditions that would affect tooth movement.
• Cases which contraindication to oral surgery.
• Previous orthodontic treatments.

Sponsors & Collaborators

• Damascus University: lead

Study Sites (1)

Orthodontic Department, University of Damascus Dental School

Damascus, 00963, Syria

Location

Related Publications (5)

• Mandelaris GA, Neiva R, Chambrone L. Cone-Beam Computed Tomography and Interdisciplinary Dentofacial Therapy: An American Academy of Periodontology Best Evidence Review Focusing on Risk Assessment of the Dentoalveolar Bone Changes Influenced by Tooth Movement. J Periodontol. 2017 Oct;88(10):960-977. doi: 10.1902/jop.2017.160781.

  PMID: 28967331 BACKGROUND

• Charavet C, Lecloux G, Bruwier A, Rompen E, Maes N, Limme M, Lambert F. Localized Piezoelectric Alveolar Decortication for Orthodontic Treatment in Adults: A Randomized Controlled Trial. J Dent Res. 2016 Aug;95(9):1003-9. doi: 10.1177/0022034516645066. Epub 2016 Apr 29.

  PMID: 27129491 BACKGROUND

• Charavet C, Lambert F, Lecloux G, Le Gall M. [Accelerated orthodontic treatment using corticotomies: what are the minimally invasive alternatives?]. Orthod Fr. 2019 Mar;90(1):5-12. doi: 10.1051/orthodfr/2019002. Epub 2019 Apr 17. French.

  PMID: 30994445 BACKGROUND

• Makedonas D, Lund H, Hansen K. Root resorption diagnosed with cone beam computed tomography after 6 months and at the end of orthodontic treatment with fixed appliances. Angle Orthod. 2013 May;83(3):389-93. doi: 10.2319/042012-332.1. Epub 2012 Oct 23.

  PMID: 23092202 BACKGROUND

• Samandara A, Papageorgiou SN, Ioannidou-Marathiotou I, Kavvadia-Tsatala S, Papadopoulos MA. Evaluation of orthodontically induced external root resorption following orthodontic treatment using cone beam computed tomography (CBCT): a systematic review and meta-analysis. Eur J Orthod. 2019 Jan 23;41(1):67-79. doi: 10.1093/ejo/cjy027.

  PMID: 29771300 BACKGROUND

Study Officials

• Mohamad Radwan Sirri, DDS MSc

  PhD student, Orthodontics Department, University of Damascus Dental School

  PRINCIPAL INVESTIGATOR

• Ahmad S Burhan, DDS MSc PhD

  Professor of Orthodontics, University of Damascus, Damascus, Syria

  STUDY DIRECTOR

• Fehmieh R Nawaya, DDS MSc PhD

  Associate Professor of Pedodontics, Syrian Private University, Damascus, Syria

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 20, 2020
• First Posted: October 26, 2020
• Study Start: March 15, 2017
• Primary Completion: November 15, 2018
• Study Completion: February 15, 2019
• Last Updated: October 26, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share

Locations

SY (1)