NCT04599530

Brief Summary

The Talaris Demonstrator is developed in continuation of previous prototypes called the AMPfoot 2.0, 3.0 and 4.0. The main goal of the experiment is to evaluate the effectiveness of TD during daily activities.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 21, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 22, 2020

Completed
3 months until next milestone

Study Start

First participant enrolled

February 1, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2021

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

December 4, 2020

Status Verified

December 1, 2020

Enrollment Period

5 months

First QC Date

October 21, 2020

Last Update Submit

December 2, 2020

Conditions

Outcome Measures

Primary Outcomes (9)

  • Biomechanical: step length

    Step Length in cm

    1 year

  • Biomechanical: cadence

    Cadence steps/min

    1 year

  • Biomechanical: step width

    Step width in cm

    1 year

  • Biomechanical: swing phases

    in % of gait cycle

    1 year

  • Biomechanical: stance phases

    in % of gait cycle

    1 year

  • Physiological: oxygen consumption

    in ml/min/kg

    1 year

  • Psychological: Visual Analogue Scale

    For Fatigue and Comfort on a scale from 0 to 10

    1 year

  • Performance: walking speed

    In meter per second

    1 year

  • Performance: duration

    secondfs

    1 year

Study Arms (4)

Biomechanical

OTHER

All experimental tasks will be evaluated on biomechanical outcome measures

Device: Talaris Demonstrator

Psychological

OTHER

All experimental tasks will be evaluated on psychological outcome measures

Device: Talaris Demonstrator

Physiological

OTHER

All experimental tasks will be evaluated on biomechanical outcome measures

Device: Talaris Demonstrator

Performance

OTHER

All experimental tasks will be evaluated on biomechanical outcome measures

Device: Talaris Demonstrator

Interventions

The Talaris Demonstrator will be evaluated during daily activities and compared to the current prosthesis

BiomechanicalPerformancePhysiologicalPsychological

Eligibility Criteria

Age25 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age: 25 - 75 years
  • Gender: men and women
  • Level of amputation: unilateral transfemoral
  • Vascular, traumatic, congenital or other cause of amputation
  • Completed the rehabilitation program, meaning that participants possess their final prosthesis
  • Medicare Functional Classification Level: K2-4
  • Participants wear their prosthesis for at least 8 hours/day

You may not qualify if:

  • Any neurological disease
  • No upper limb or bilateral amputation
  • Stump pain or bad fit of the socket

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Model Details: A within Subject Design
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctorandus

Study Record Dates

First Submitted

October 21, 2020

First Posted

October 22, 2020

Study Start

February 1, 2021

Primary Completion

June 30, 2021

Study Completion

December 31, 2021

Last Updated

December 4, 2020

Record last verified: 2020-12

Data Sharing

IPD Sharing
Will not share