NCT04591015

Brief Summary

The COVID-19 pandemic has triggered extremely high hospitalization rates where mitigation strategies are urgently necessary to aid vulnerable Hispanic and Latino populations who are experiencing health disparities as well as high type 2 diabetes (T2D) prevalence with poor clinical outcomes when compared to non-Hispanic populations. The supplemental Dulce Digital-COVID Aware (DD-CA) intervention addresses specific barriers in diverse underserved Hispanic and Latino communities to improve glucose control and lower transmission of COVID-19 during a highly vulnerable period post hospitalization discharge, to reduce hospital readmission rates. This supplement will integrate COVID educational messaging with glucose management messaging within a low-cost, easily adoptable digital texting platform and offer critical information in a culturally and linguistically relevant manner to address specific barriers in diverse underserved communities.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
172

participants targeted

Target at P50-P75 for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started Feb 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 5, 2020

Completed
14 days until next milestone

First Posted

Study publicly available on registry

October 19, 2020

Completed
4 months until next milestone

Study Start

First participant enrolled

February 1, 2021

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2022

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

September 28, 2023

Completed
Last Updated

June 18, 2025

Status Verified

June 1, 2025

Enrollment Period

1.6 years

First QC Date

October 5, 2020

Results QC Date

August 30, 2023

Last Update Submit

June 2, 2025

Conditions

Keywords

Type 2 DiabetesCOVID-19

Outcome Measures

Primary Outcomes (3)

  • Hospital Readmission Rate Within 30 Days of Discharge

    Number of Participants With at Least 1 Hospital Readmission Within 30 Days After Enrollment, analyzed for full study sample

    Within 30 days of discharge

  • Glycosylated Hemoglobin (HbA1c) - Change From Baseline to 90 Days

    Change in Glycosylated Hemoglobin (HbA1c) 90 days from baseline. A negative mean indicates positive change in HbA1c.

    90 days from baseline

  • Glycosylated Hemoglobin (HbA1c) - Change From Baseline to 180 Days

    Change in Glycosylated Hemoglobin (HbA1c) 180 days from baseline. A negative mean indicates positive change in HbA1c.

    180 days from baseline

Secondary Outcomes (17)

  • Hospital Readmission Rate Within 90 Days of Discharge

    Within 90 days of discharge

  • Diabetes Distress Scale - Change From Baseline to 90 Days

    90 days from baseline

  • Diabetes Distress Scale - Change From Baseline to 180 Days

    180 days from baseline

  • Summary of Diabetes Self-Care Activities - Diet - Change From Baseline to 90 Days

    90 days from baseline

  • Summary of Diabetes Self-Care Activities - Exercise - Change From Baseline to 90 Days

    90 days from baseline

  • +12 more secondary outcomes

Study Arms (2)

DD-CA

EXPERIMENTAL

In the DD-CA arm, participants will be offered a proven digital texting platform in their language of preference (Spanish/English) as part of the diabetes transitions discharge program with added COVID support messages.

Behavioral: Hospital: DD-CA

Usual Care (UC)

ACTIVE COMPARATOR

UC participants will not receive the added COVID support messages, both arms will have a referral placed to the Diabetes Transitions Service (DTS) as part of usual care at the time of discharge.

Behavioral: Hospital: Usual Care (UC)

Interventions

Hospital: DD-CABEHAVIORAL

In the DD-CA group, participants will be offered a proven digital texting platform in their language of preference (Spanish/English) as part of the diabetes transitions discharge program with educational, motivational and medication adherence messaging that is currently an arm of our parent DD-ME grant with added COVID support messages that provide information addressing identified barriers in Hispanic underserved communities (e.g. obtaining testing supplies and medications, accessing routine medical care, and completing other important diabetes self-management behaviors such as healthful eating, exercise, social distancing, quarantine, and stay-at-home/lockdown guidelines).

DD-CA

In the UC group, participants will not receive the added COVID support messages, both groups will have a referral placed to the Diabetes Transitions Service (DTS) at the time of discharge as part of usual care. Participants will be contacted by a peer health coach following protocol to coordinate care with outpatient health and other community resources.

Usual Care (UC)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Are a patient admitted to a Scripps Mercy Hospital,
  • Consider yourself Hispanic/Latino, of any race
  • Are 18 years of age or older,
  • Speak English or Spanish,
  • Have type 2 diabetes and A1c ≥ 7% in the last 90 days, and
  • Have a cellphone that can receive/send text messages.

You may not qualify if:

  • Are pregnant,
  • Are currently participating in another diabetes or COVID-19 related study, or

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Scripps Mercy Hospital Chula Vista

Chula Vista, California, 91910, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2COVID-19

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesPneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Results Point of Contact

Title
Athena Philis-Tsimikas, MD, Co-Principal Investigator
Organization
Scripps Health

Study Officials

  • Athena Philis-Tsimikas, MD

    Scripps Whittier Diabetes Institute

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Corporate Vice President

Study Record Dates

First Submitted

October 5, 2020

First Posted

October 19, 2020

Study Start

February 1, 2021

Primary Completion

August 31, 2022

Study Completion

August 31, 2022

Last Updated

June 18, 2025

Results First Posted

September 28, 2023

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations