NCT04585555

Brief Summary

The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using electronic medical records and data streams via the Accuryn Monitoring System.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2017

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 10, 2017

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 6, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 5, 2019

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

August 21, 2020

Completed
2 months until next milestone

First Posted

Study publicly available on registry

October 14, 2020

Completed
Last Updated

February 4, 2021

Status Verified

February 1, 2021

Enrollment Period

2.2 years

First QC Date

August 21, 2020

Last Update Submit

February 2, 2021

Conditions

Outcome Measures

Primary Outcomes (6)

  • Urine Output (UO)

    High accuracy Urine Output (mL/hour) while on a urinary catheter, and estimated UO while not on a urinary catheter

    30 days

  • Intra-Abdominal Pressure (IAP)

    Intra-Abdominal Pressure (mmHg) trending while on a urinary catheter, as well as active measurements taken by clinician

    30 days

  • Temperature (T)

    Temperature (degrees Celsius) trending during hospital stay

    30 days

  • Intraabdominal Hypertension (IAH)

    Intra-abdominal pressure (IAP) above 12 mm Hg (timepoint and duration)

    30 days

  • Abdominal Compartment Syndrome (ACS)

    Intra-abdominal pressure (IAP) above 20 mm Hg with new organ dysfunction or failure (timepoint and duration)

    30 days

  • Acute Kidney Injury (AKI)

    % of patients diagnosed with AKI, and hospitalization day of diagnosis. AKI diagnosed per KDIGO criteria (Stage 1 to 3)

    30 days

Study Arms (1)

Accuryn Monitoring System

Observational only (no intervention). Patients undergoing cardiovascular surgical intervention(s) monitored with the Accuryn Monitoring System (per standard of care) during their hospital stay.

Device: Accuryn Monitoring System

Interventions

The Accuryn Monitoring System is a novel Foley catheter and monitoring device capable of detecting physiologic changes in vital signs via sensors within the catheter system. These data are captured non-invasively, continuously, and at a high frequency.

Accuryn Monitoring System

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients undergoing cardiovascular surgical intervention(s) monitored with the Accuryn Monitoring System (per standard of care) during their hospital stay.

You may qualify if:

  • Adult (age ≥ 18).
  • Monitored on the Accuryn® Monitoring System during hospital stay.
  • Patient is undergoing cardiovascular surgical intervention(s).

You may not qualify if:

  • \. The patient is unsuitable for the study, in the opinion of the investigator. This may include vulnerable patient populations such as prisoners or those detained in a penal institution.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Emory University Hospital

Atlanta, Georgia, 30322, United States

Location

MeSH Terms

Conditions

Acute Kidney InjuryIntra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesCompartment SyndromesMuscular DiseasesMusculoskeletal DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Amit Prabhakar, MD

    Emory University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
30 Days
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 21, 2020

First Posted

October 14, 2020

Study Start

July 10, 2017

Primary Completion

October 6, 2019

Study Completion

November 5, 2019

Last Updated

February 4, 2021

Record last verified: 2021-02

Locations