NCT04584619

Brief Summary

The aim of this observational post-marketing study is to provide additional information on the safety and effectiveness of Idys™ TLIF 3DTi at up to 24 months post transforaminal lumbar fusion in usual surgical practice.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Oct 2020

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 30, 2020

Completed
1 day until next milestone

Study Start

First participant enrolled

October 1, 2020

Completed
13 days until next milestone

First Posted

Study publicly available on registry

October 14, 2020

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

November 29, 2021

Status Verified

November 1, 2021

Enrollment Period

3 years

First QC Date

September 30, 2020

Last Update Submit

November 25, 2021

Conditions

Keywords

SpineInterbody fusion device

Outcome Measures

Primary Outcomes (1)

  • Evolution of the Fusion rate

    Evolution of the radiological assessment of bony fusion at 3 different time point

    6 months, 12 months, 24 months postoperatively

Secondary Outcomes (6)

  • Adverse events

    Up to 24 months postoperatively

  • Evolution of the Patient Disability

    Preoperatively and then 6 weeks, 6 months, 12 months and 24 months postoperatively

  • Evolution of the Patient Pain

    Preoperatively and then 6 weeks, 6 months, 12 months and 24 months postoperatively

  • Radiologic Outcomes - Evolution of the lordosis angles (degree)

    Preoperatively and then 6 weeks, 6 months, 12 months and 24 months postoperatively

  • Radiologic Outcomes - Evolution of the Intervertebral Height (mm)

    Preoperatively and then 6 weeks, 6 months, 12 months and 24 months postoperatively

  • +1 more secondary outcomes

Interventions

Posterior fusion of the lumbar spine with Clariance Idys TLIF 3DTi interbody fusion device used in conjunction with a posterior fixation system (pedicle screws and rod).

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patient who need fusion of spinal lumbar segments

You may qualify if:

  • English Speaking patients
  • Patient with skeletal maturity
  • Patient with
  • degenerative disc disease at one or two levels from L2 to S1 and/or
  • grade 1 spondylolisthesis
  • Surgical treatment with Idys TLIF 3DTi interbody fusion device used in conjunction with a posterior fixation system (pedicle screws and rod).

You may not qualify if:

  • Off-label indications.
  • Any medical or surgical condition which would preclude the potential benefit of spinal implant surgery.
  • Any patient having a prior fusion at the level to be treated.
  • Any patient being vulnerable
  • Non-English speakers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brazos Spine

College Station, Texas, 77845, United States

Location

MeSH Terms

Conditions

Intervertebral Disc Degeneration

Condition Hierarchy (Ancestors)

Spinal DiseasesBone DiseasesMusculoskeletal Diseases

Study Officials

  • Mukund Gundanna, Dr

    Brazos Spine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 30, 2020

First Posted

October 14, 2020

Study Start

October 1, 2020

Primary Completion

September 30, 2023

Study Completion

December 31, 2023

Last Updated

November 29, 2021

Record last verified: 2021-11

Data Sharing

IPD Sharing
Will not share

Locations