Postoperative Pain Endodontic Retreatment
Incidence Postoperative Pain After Single Visit Versus Two Visit Nonsurgical Endodontic Retreatment
1 other identifier
interventional
62
0 countries
N/A
Brief Summary
To compare the incidence of post-operative pain after single-visit versus two-visit non-surgical endodontic retreatment.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Oct 2020
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 5, 2020
CompletedStudy Start
First participant enrolled
October 1, 2020
CompletedFirst Posted
Study publicly available on registry
October 9, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedOctober 9, 2020
October 1, 2020
7 months
May 5, 2020
October 7, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Incidence and intensity of postoperative
Evaluate incidence and intensity of postoperative pain at 6,12,24, 48hours , and one week using numerical visual scale (NRS) after each visit endodontic retreatment
At one week after each visit
Secondary Outcomes (1)
Number of analgesic tablets
baseline
Study Arms (2)
group 1 Non-surgical endodontic retreatment in single visit
EXPERIMENTALSingle visit treatments have gained more popularity. Completing the treatment in a single appointment has many advantages including reduction in treatment time and cost, lower risk of micro leakage and recontamination of root canals between appointments
group 2 Non-surgical endodontic retreatment in Two-visit
ACTIVE COMPARATORTwo-visit endodontic treatment with intra-canal medication was traditionally found to be effective in decreasing the number of flare-up in all retreatment cases and in reducing postoperative pain of previously symptomatic teeth
Interventions
Full medical and dental history using a schematic dental chart, will be obtained from all patients treated during this study.
Eligibility Criteria
You may qualify if:
- Clinically asymptomatic.
- Previously treated teeth in need of retreatment due to leakage and/or improper filling.
- No periapical radiolucency.
- No percussion pains.
- Age 20 - 45.
- Premolar teeth.
- Male \& female.
You may not qualify if:
- Complicating compromised patient.
- Tenderness to percussion and acute apical abscess.
- Presence of an associated sinus tract.
- Presence of swelling in adjacent soft tissue.
- Teeth with periodontal pathologies or mobility.
- Teeth representing root fracture.
- Pregnant women.
- If analgesics or antibiotics have been administrated by the patient during the past 24 hours.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Related Publications (1)
Erdem Hepsenoglu Y, Eyuboglu TF, Ozcan M. Postoperative Pain Intensity after Single- versus Two-visit Nonsurgical Endodontic Retreatment: A Randomized Clinical Trial. J Endod. 2018 Sep;44(9):1339-1346. doi: 10.1016/j.joen.2018.05.017. Epub 2018 Jul 24.
PMID: 30054099BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principle investigator
Study Record Dates
First Submitted
May 5, 2020
First Posted
October 9, 2020
Study Start
October 1, 2020
Primary Completion
May 1, 2021
Study Completion
June 1, 2021
Last Updated
October 9, 2020
Record last verified: 2020-10