Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs

NCT04557592 | Completed

• 1 other identifier: 2020/110
• Study Type: observational
• Target: 98
• Locations: 1 country
• Sites: 1

Brief Summary

The GAITRite® system is an instrumented with resistive pressure sensors gait analyzer. It was first validate in 2001 against paper-and-pencil (intraclass correlation coefficient \[ICC\] \> 95%) for spatial measures and against video-based (ICC \> 93%) for temporal measures, and was thus a reliable tools to measure step lengths and times in both walkway center and left-of-center measurements. It was considered as one of the gold standards in gait analyses. This gait analyze system may distinguish prospectively faller and non-faller older adults, but it can detect spatial, temporal, and spatiotemporal measures of gait and greater variability of gait parameters which were associated with and predictive of both global- and domain-specific cognitive decline. Moreover, spatiotemporal gait parameters analyzed using GAITRite® were more disturbed in the advanced stages of dementia, and more affected in the non-AD dementia than in AD suggesting that quantitative gait parameters could be used as a surrogate marker for improving the diagnosis of dementia. Nevertheless, GAITRite® is not a unique system and it comprises different walkways. One of these technologies was a roll-up system (platinum plus classic, RE, Basic and Safari), and the other was a system composed by a changeable association of plates (CIRFACE). In order to ensure a good comparability between studies using these different walkways, it appears important to compare the performances of these walkways in gait analysis. Thus, the main aim of this study was to compare the performances in gait analyze between the GAITRite® platinum plus classic and the GAITRite® CIRFACE among older adults. Secondary aims were to compare these parameters among patients with cognitive complaint, minor or major neurocognitive disorder (NCD) related to Alzheimer disease.

Conditions

Gait Apraxia; Alzheimer Disease; Impaired Cognition

Outcome Measures

Primary Outcomes (3)

• Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices

  in the sub-group: Absence of cognitive impairment

  baseline

• Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices

  in the sub-group: Minor Neurocognitive Disorder

  baseline

• Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices

  in the sub-group: Major Neurocognitive Disorder

  baseline

Eligibility Criteria

• Age: 74 Years+
• Sex: all
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All consecutive patients meeting the eligibility criteria over the study period.

You may qualify if:

• Age ≥ 75 years
• Gait analysis performed with the two walkways superimposed during a consultation or day hospitalization

You may not qualify if:

• Opposition to the use of the information collected for research purposes

Sponsors & Collaborators

• University Hospital, Angers: lead

Study Sites (1)

Angers University Hospital

Angers, 49933, France

Location

Related Publications (1)

• Sacco G, Ben-Sadoun G, Gautier J, Simon R, Goupil M, Laureau P, Terrien J, Annweiler C. Comparison of spatio-temporal gait parameters between the GAITRite(R) platinum plus classic and the GAITRite(R) CIRFACE among older adults: a retrospective observational study. BMC Geriatr. 2023 Mar 7;23(1):132. doi: 10.1186/s12877-023-03811-7.

  PMID: 36882705 DERIVED

MeSH Terms

Conditions

Gait Apraxia; Alzheimer Disease; Cognition Disorders

Condition Hierarchy (Ancestors)

Gait Disorders, Neurologic; Neurologic Manifestations; Nervous System Diseases; Apraxias; Psychomotor Disorders; Neurobehavioral Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Dementia; Brain Diseases; Central Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 15, 2020
• First Posted: September 21, 2020
• Study Start: June 17, 2019
• Primary Completion: February 26, 2020
• Study Completion: February 26, 2020
• Last Updated: September 21, 2020

Record last verified: 2020-09

Locations

FR (1)