NCT04556591

Brief Summary

The purpose of this study is to test whether personalized messages from an easy-to-use mobile app improve mood and stress among care partners and to see if care partners like using the app.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 14, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 21, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

November 5, 2020

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 7, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 7, 2021

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

March 21, 2023

Completed
Last Updated

March 21, 2023

Status Verified

February 1, 2023

Enrollment Period

7 months

First QC Date

September 14, 2020

Results QC Date

May 31, 2022

Last Update Submit

February 20, 2023

Conditions

Keywords

DepressionInsomniaStress related disordersAnxiety

Outcome Measures

Primary Outcomes (1)

  • Feasibility and Acceptability as Measured by the Percentage of Agree or Strongly Agree Responses to the Individual Items on the Feasibility Questionnaire

    Items are scaled from 1 to 5 to indicate the level of agreement, where "1" indicates "strong disagreement" and "5" indicates "strong agreement". Percentages shown are the combined percentage of participants who selected "agree" or "strongly agree" or their equivalent (as labeled).

    3 months of wearing the Fitbit and completing the surveys

Secondary Outcomes (2)

  • Attrition as Measured by the Percent of Participants Completing the Study

    3 months of wearing the Fitbit and completing the surveys

  • Adherence as Measured by the Percentage of Contributed Data Over the Course of the Study

    3 months of wearing the Fitbit and completing the surveys

Study Arms (2)

Control

ACTIVE COMPARATOR

Participants will wear the Fitbit® and provide daily reports of health related quality of life (HRQOL) over a three-month (90 day) period (without the personalized feedback).

Behavioral: Control

Just-in-time adaptive intervention (JITAI)

EXPERIMENTAL

Participants will wear the Fitbit®, provide daily reports of health related quality of life (HRQOL) and receive personalized pushes over a three-month (90 day) period.

Behavioral: Just-in-time adaptive intervention (JITAI)

Interventions

JITAI is an emerging intervention that incorporates passive mobile sensor data feedback (sleep and activity \[step\] data from a Fitbit ®), and real-time self-reporting of HRQOL via a study specific app called CareQOL to provide personalized feedback via app alert.

Just-in-time adaptive intervention (JITAI)
ControlBEHAVIORAL

Participants will wear the Fitbit® and provide daily reports of HRQOL over a three-month (90 day) period

Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Provide emotional, physical, and/or financial support/assistance to an individual with spinal cord injury (SCI), Huntington's Disease (HD), or hematopoietic cell transplantation (HCT)
  • Have access to necessary resources for participating in a technology-based intervention (smartphone/tablet and internet access) and be willing to use their personal equipment/internet for this study, including downloading the study app and the Fitbit® app on their mobile device
  • Care partners of persons with HD: Be caring for an adult (18 years or older) with a clinical diagnosis of HD
  • Care partners of persons with SCI: Be caring for an adult (18 years or older) that is ≥1 post-injury and sustained a medically documented SCI at age 16 or older
  • Care partners of persons with HCT: Be caring for an adult (18 years or older) who is receiving, has received or is scheduled to receive HCT

You may not qualify if:

  • Is a professional, paid caregiver (e.g., home health aide)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Michigan

Ann Arbor, Michigan, 48109, United States

Location

Related Publications (4)

  • Wang J, Wu Z, Choi SW, Sen S, Yan X, Miner JA, Sander AM, Lyden AK, Troost JP, Carlozzi NE. The Dosing of Mobile-Based Just-in-Time Adaptive Self-Management Prompts for Caregivers: Preliminary Findings From a Pilot Microrandomized Study. JMIR Form Res. 2023 Sep 14;7:e43099. doi: 10.2196/43099.

  • Carlozzi NE, Choi SW, Wu Z, Sen S, Troost J, Lyden AK, Miner JA, Graves C, Sander AM. The reliability and validity of the TBI-CareQOL system in four diverse caregiver groups. J Patient Rep Outcomes. 2023 Jun 26;7(1):57. doi: 10.1186/s41687-023-00602-x.

  • Carlozzi NE, Choi SW, Wu Z, Troost JP, Lyden AK, Miner JA, Graves CM, Wang J, Yan X, Sen S. An app-based just-in-time-adaptive self-management intervention for care partners: The CareQOL feasibility pilot study. Rehabil Psychol. 2022 Nov;67(4):497-512. doi: 10.1037/rep0000472.

  • Carlozzi NE, Choi SW, Wu Z, Miner JA, Lyden AK, Graves C, Wang J, Sen S. An App-Based Just-in-Time Adaptive Self-management Intervention for Care Partners (CareQOL): Protocol for a Pilot Trial. JMIR Res Protoc. 2021 Dec 9;10(12):e32842. doi: 10.2196/32842.

MeSH Terms

Conditions

DepressionSleep Initiation and Maintenance DisordersAnxiety Disorders

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Results Point of Contact

Title
Dr. Noelle E. Carlozzi
Organization
University of Michigan

Study Officials

  • Noelle Carlozzi, Ph.D

    University of Michigan

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Model Details: This behavioral trial will use a two-arm randomized controlled design.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Physical Medicine and Rehabilitation

Study Record Dates

First Submitted

September 14, 2020

First Posted

September 21, 2020

Study Start

November 5, 2020

Primary Completion

June 7, 2021

Study Completion

June 7, 2021

Last Updated

March 21, 2023

Results First Posted

March 21, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will share

Participant data collected during the trial, after de-identification, will be available for sharing with individuals in the scientific community, upon request. The data will be available after the acceptance for publication of the main findings from the final dataset. The University of Michigan Project Manager will coordinate requests for data and maintain documentation for requests and distributions. An institutional data use agreement will be required before data is shared.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
The data will be available after the acceptance for publication of the main findings from the final dataset.
Access Criteria
Data is available upon request to the project manager. Requests for data sharing should be emailed to PMR-CODAlab@med.umich.edu.

Locations