NCT04555421

Brief Summary

To examine the effect of using Lumen on metabolic parameters and anthropometric variables. This will be done from baseline to the end of a 12 weeks intervention in adults with prediabetes..

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 16, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 18, 2020

Completed
13 days until next milestone

Study Start

First participant enrolled

October 1, 2020

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2021

Completed
Last Updated

September 18, 2020

Status Verified

September 1, 2020

Enrollment Period

1 year

First QC Date

September 16, 2020

Last Update Submit

September 16, 2020

Conditions

Outcome Measures

Primary Outcomes (2)

  • Weight change

    % weight change

    from baseline to 12 weeks

  • Fat percentage

    % change in fat percentage

    from baseline to 12 weeks

Secondary Outcomes (3)

  • Blood tests changes - glycemic control

    from baseline to 12 weeks

  • Blood tests changes- lipid panel change

    from baseline to 12 weeks

  • Blood tests changes - glycemic control

    from baseline to 12 weeks

Study Arms (1)

Lumen device usage and diet guidelines

EXPERIMENTAL
Device: Lumen

Interventions

LumenDEVICE

Subjects will use the Lumen device and mobile phone application, which will guide their diet, sleep, and routines according to their Lumen measurements. In addition, a Lumen coach will be assigned to the subjects, and they will have a 30 minutes video call with the coach during the familiarization stage, in order to acquaint them with Lumen and explain them about the application and the nutritional guidance.

Lumen device usage and diet guidelines

Eligibility Criteria

Age25 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • BMI ≥ 27 to ≤ 40 HbA1c ≥ 5.7% to ≤6.4% Fasting glucose ≥ 100 mg/dl to ≤ 125 mg/dl Not treated with diabetes-related medications

You may not qualify if:

  • Medications:
  • Insulin and medications for glycemic control
  • Antipsychotics
  • Diuretics
  • Anti-retrovirals
  • Corticosteroids
  • Oncologic treatment
  • Thyroid hormones (if endocrinological control is good, can be included).
  • Conditions:
  • Previous diagnosis of diabetes
  • G6PD deficiency
  • Renal disease
  • Hepatic disease
  • Pregnancy
  • Hematological (anemia)
  • +12 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Institute of Endocrinology, Metabolism and Hypertension

Tel Aviv, 64239, Israel

Location

MeSH Terms

Conditions

Prediabetic StateOverweightObesity

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesOvernutritionNutrition DisordersBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Roy Eldor, MD; PhD

CONTACT

Assaf Buch, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 16, 2020

First Posted

September 18, 2020

Study Start

October 1, 2020

Primary Completion

October 1, 2021

Study Completion

October 1, 2021

Last Updated

September 18, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will not share

Locations