Pharmacists Improving Refugees' Adherence and Knowledge of Their Chronic Medications

NCT04554810 | Completed DMC

• 1 other identifier: MOH-REC-160079
• Study Type: interventional
• Target: 106
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study is a randomized, controlled, single-blinded clinical study which conducted over six months (May to October 2016) in different Jordanian cities, where most of Syrian refugees reside. The primary aim of this study was to assess refugees' adherence and knowledge of their chronic medications, and impact of the medication management review (MMR) service delivered by a clinical pharmacist on their adherence and knowledge of their chronic medications three months following delivering the service. An informed consent form was signed by all participants who accepted to participate (n=106). Participants were then randomized into intervention and control groups. The first group would have received the medication management review service during the study period, while the to the other group directly after the study was completed (after three months' time). Two validated questionnaire were used in the study for assessment; adherence to medications questionnaire and Knowledge about chronic medications questionnaire. These questionnaire were filled by tha patients at baseline and follow up home visits.

Conditions

Diabetes; Hypertension; Dyslipidemias; Cardiac Disease; Asthma

Keywords

Refugees; Medication management review; Adherence; Pharmaceutical care; chronic medication; Jordan; Universal health coverage; Sustainable development goal

Outcome Measures

Primary Outcomes (2)

• Adherence to medications scores

  how often the patient during the last month forgot to take his/her medication/s, skipped it, stopped it when feeling better, stopped it when feeling worse or stopped it when they experienced a side effect. The measurement scale used in this questionnaire was scored at 0 (never), 1 (rarely), 2 (sometimes), 3 (often) and 4 (always). Hence, adherence was analysed as a continuous scale out of 32. Higher scores indicted lower adherence by the patient.

  3 months

• Knowledge about chronic medications scores

  The questionnaire consisted of five questions related to patients' medications including 1- scientific medication name, 2- generic medication name, 3- how, 4- when, and 5- why was the patient taking each medication. The knowledge about medications was analysed as a continuous scale out of five. Higher scores indicated less knowledge about one's medication therapy.

  3 months

Study Arms (2)

Intervention group

ACTIVE COMPARATOR

Intervention group participants are the refugees who received the medication management review service and pharmacist's counselling. They have been assessed at baseline and at follow-up after 3 months) home visits.

Other: Medication Management Service

Control group

NO INTERVENTION

Control group participants are the refugees who did not received the medication management review service and no pharmacist's counselling wsa provided to them during the study period. They have been assessed at baseline and at follow-up (after 3 months) home visits.

Interventions

Medication Management Service OTHER

Medication review was delivered to the Syrian refugees by accredited pharmacists at the baseline visit. This followed by identifying the treatment-related problems (TRP) by the clinical pharmacist, and correction of the approved TRPs by the corresponding physicians and finally convey these changes in medications to the patients. In addition, counselling and education were delivered to the refugees' patients in the base line visit.

Intervention group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• being Syrian refugee ≥ 18 years, living in Jordan for more than six months prior to study recruitment and intending to stay for the whole study period
• having one chronic condition at least or taking 5 or more medications or taking more than 12 doses of a medication per day

You may not qualify if:

• Patients with cognitive or sensory impairment that may prevent conducting the interview.
• Patients who are planning to travel within the next six months after the baseline home-visit
• Patients who are not capable of reading or writing

Sponsors & Collaborators

• Prof. Iman Basheti: lead

Related Publications (1)

• Alalawneh M, Berardi A, Nuaimi N, Basheti IA. Improving Syrian refugees' knowledge of medications and adherence following a randomized control trial assessing the effect of a medication management review service. PLoS One. 2022 Oct 14;17(10):e0276304. doi: 10.1371/journal.pone.0276304. eCollection 2022.

  PMID: 36240214 DERIVED

MeSH Terms

Conditions

Diabetes Mellitus; Hypertension; Dyslipidemias; Heart Diseases; Asthma

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Vascular Diseases; Cardiovascular Diseases; Lipid Metabolism Disorders; Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• I A Basheti

  Applied Science University, Amman, Jordan

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor in Clinical Pharmacy

Study Record Dates

• First Submitted: September 8, 2020
• First Posted: September 18, 2020
• Study Start: May 10, 2015
• Primary Completion: December 10, 2015
• Study Completion: January 30, 2016
• Last Updated: September 18, 2020

Record last verified: 2020-09