Heavy Lifting Strength Training in Head and Neck Cancer Survivors

NCT04554667 | Completed Phase 1

• 1 other identifier: 20-0169
• Study Type: interventional
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

The LIFTING trial will examine the feasibility and safety of a heavy lifting strength training (HLST) program in head and neck cancer survivors (HNCS) at least 1 years post surgical neck dissection. The trial will determine whether this training style is safe and feasible in HNCS. Physical and psychosocial changes will also be reported.

Conditions

Cancer of Head and Neck

Keywords

surgery; neck dissection; strength training; survivors; exercise

Outcome Measures

Primary Outcomes (3)

• Recruitment Rate

  Recruitment rate (with reasons for refusal). Recruitment minimum: 15 participants Recruitment maximum: 20 participants Higher number= better and more data

  Over 12 weeks

• Muscular Strength

  Change in muscular strength from baseline to postintervention with be assessed using maximal strength tests. Minimum: none Maximum: none Higher score= better strength

  Changes from baseline to 12 weeks

• Program Adherence

  Program adherence minimum: 80% Program adherence maximum: 100% Higher score= better adherence

  Over 12 weeks

Secondary Outcomes (15)

• Physical functioning

  Changes from baseline to 12 weeks

• Fear of cancer recurrence

  Changes from baseline to 12 weeks

• Post Traumatic Growth after cancer

  Changes from baseline to 12 weeks

• Waist to hip ratio (body composition)

  Changes from baseline to 12 weeks

• Anxiety

  Changes from baseline to 12 weeks

Study Arms (1)

Exercise Intervention

EXPERIMENTAL

Single exercise arm

Behavioral: Exercise Intervention

Interventions

Exercise Intervention BEHAVIORAL

Heavy Lifting Strength Training

Exercise Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• previously diagnosed with any subtype and stage of head and neck cancer
• at least one year post surgical neck dissection for head and neck cancer and showing full shoulder range of motion or recovery of the spinal accessory nerve
• adults ages 18 and older
• no unmanaged medical conditions, alcohol, and drug abuse
• approved for a heavy lifting strength training program by the treating surgeon and a certified exercise physiologist
• ability to understand and communicate in English

You may not qualify if:

• having comorbidities or uncontrolled medical conditions that their referred clinicians indicate as inappropriate to participate in exercise

Sponsors & Collaborators

• University of Alberta: lead

Study Sites (1)

University of Alberta

Edmonton, Alberta, T6G 2H9, Canada

Location

Related Publications (1)

• Ntoukas SM, McNeely ML, Seikaly H, O'Connell D, Courneya KS. Feasibility and safety of Heavy Lifting Strength Training in Head and Neck Cancer survivors post-surgical neck dissection (the LIFTING trial). Support Care Cancer. 2023 May 22;31(6):348. doi: 10.1007/s00520-023-07815-2.

  PMID: 37212970 DERIVED

MeSH Terms

Conditions

Head and Neck Neoplasms; Motor Activity

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Behavior

Study Officials

• Kerry S Courneya, PhD

  University of Alberta

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Single arm, safety and feasibility trial.

Study Record Dates

• First Submitted: September 11, 2020
• First Posted: September 18, 2020
• Study Start: November 24, 2020
• Primary Completion: July 31, 2022
• Study Completion: July 31, 2022
• Last Updated: September 6, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)