Electrolyte State in Patients With COVID-19

NCT04539834 | Completed

• 1 other identifier: (ZU-IRB#: 6328-23-8-2020)
• Study Type: observational
• Target: 983
• Locations: 1 country
• Sites: 1

Brief Summary

Initial case reports and cohort studies have described many clinical characteristics of patients with coronavirus disease 2019 (COVID-19), an emerging infectious disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In early COVID-19 studies, some evidence has been provided that electrolyte disorders may also be present upon patients' presentation, including sodium, potassium, chloride and calcium abnormalities the aim of the study is Identification of elements that affect COVID-19 pathology to improve survival and decrease mortality rate.

Conditions

Electrolyte Imbalance

Keywords

Electrolytes; COVID-19

Outcome Measures

Primary Outcomes (1)

• electrolytes disturbances in patients with COVID-19

  Serum Electrolytes (Na, K, Ca, Cl, Ph, Mg) abnormality in COVID 19 patients laboratory results in the different stages of the disease

  4 months

Secondary Outcomes (1)

• To asses the relation of the electrolyte disturbances with the severity of COVID-19 infection.

  4 months

Interventions

electrolytes OTHER

measuring level of electrolytes

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients ≥ 18 years old with diagnosis of COVID-19 infection who admitted to Isolation hospital of Zagazig University Hospitals during the period from 1 May 2020 to 1 August 2020.

You may qualify if:

• Patients ≥ 18 years old who were confirmed by the real-time PCR on the respiratory tract samples as positive of SARS-CoV-2.

You may not qualify if:

• Patients who had other causes of electrolyte disturbances (9):
• Chronic organ dysfunction (e.g., hepatic or renal dysfunction),
• Terminal cancer, immunodeficiency, and
• Patients with a history of long-term use of hormones \& Diuretics were excluded.

Sponsors & Collaborators

• Zagazig University: lead

Study Sites (1)

Zagazig University

Zagazig, 055, Egypt

Location

MeSH Terms

Conditions

COVID-19

Interventions

Electrolytes

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Inorganic Chemicals

Study Officials

• Tarek Hamdy, MD

  lecturer of Chest diseases, Faculty of Medicine, Zagazig University

  STUDY DIRECTOR

• Hadeer El Shahaat, master degree

  Assistant lecturer of Chest diseases, Faculty of Medicine, Zagazig University

  PRINCIPAL INVESTIGATOR

• Ahmed Abdulsaboor, MD

  Clinical Pathology Department, Faculty of Medicine, Zagazig University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer

Study Record Dates

• First Submitted: September 1, 2020
• First Posted: September 7, 2020
• Study Start: May 1, 2020
• Primary Completion: August 1, 2021
• Study Completion: October 30, 2021
• Last Updated: November 23, 2021

Record last verified: 2021-11

Locations

EG (1)