24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

NCT05550467 | Completed

• 1 other identifier: 2015BAI12B06-03
• Study Type: observational
• Target: 10,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine glucose, urine protein, urine retinol) and adverse prognosis in patients with chronic kidney disease

Conditions

Chronic Kidney Diseases; Electrolyte Imbalance

Outcome Measures

Primary Outcomes (2)

• Kidney disease progression

  eGFR decline \> 50%; dialysis; kidney transplant

  2014.1.1-2022.7.31

• Death

  All cause death

  2014.1.1-2022.7.31

Secondary Outcomes (1)

• Cardiovascular disease

  2014.1.1-2022.7.31

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Age ≥ 18 years, chronic kidney disease patients without kidney replacement therapy who had 24-h urine eletrocyte tests.

You may qualify if:

• Our study is a retrospective cohort study. The study included patients with adult（Age≥18years）CKD who were hospitalized in the Department of Nephrology, First Medical Center of Chinese PLA General Hospital from January 2014 to July 2022. Patients with CKD who had one or more 24-hour urinary electrolyte excretion tests at intervals of more than three months were included in the subgroup analysis.

You may not qualify if:

• Patients with hemodialysis therapy and urine volume less than 500ml were excluded.

Sponsors & Collaborators

• Chinese PLA General Hospital: lead

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: September 19, 2022
• First Posted: September 22, 2022
• Study Start: January 1, 2014
• Primary Completion: July 30, 2022
• Study Completion: July 31, 2022
• Last Updated: September 22, 2022

Record last verified: 2022-09