NCT04532190

Brief Summary

Attention-Deficit/Hyperactivity Disorder (ADHD) is characterized by poor attention, impulsivity, hyperactivity and emotional-motivational dysregulation. Here, we will test if theta burst repetitive transcranial magnetic stimulation (rTMS) can reduce the symptoms of ADHD.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
21mo left

Started Nov 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress21%
Nov 2025Dec 2027

First Submitted

Initial submission to the registry

August 25, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 31, 2020

Completed
5.2 years until next milestone

Study Start

First participant enrolled

November 24, 2025

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2027

Last Updated

November 25, 2025

Status Verified

November 1, 2025

Enrollment Period

2.1 years

First QC Date

August 25, 2020

Last Update Submit

November 19, 2025

Conditions

Attention-Deficit/Hyperactivity Disorder (ADHD)

Keywords

Attention-Deficit/Hyperactivity Disorder (ADHDRepetitive transcranial magnetic stimulation (rTMS)

Outcome Measures

Primary Outcomes (1)

  • TEACH-2

    Test of everyday attention in children - 2. Direct assessment of attention abilities in children.

    Baseline to week 5

Secondary Outcomes (2)

  • SNAP-18

    5 weeks and 52 weeks.

  • PedsQL

    Baseline to week 5

Study Arms (1)

Active rTMS

EXPERIMENTAL

Active repetitive TMS

Device: rTMS

Interventions

rTMSDEVICE

Repetitive transcranial magnetic stimulation (rTMS)

Active rTMS

Eligibility Criteria

Age9 Years - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Diagnosis of ADHD
  • years old
  • IQ greater than 80
  • English fluency (to enable consent/assent)
  • If on medication, must have been on the same type and dosage for at least 3 months.

You may not qualify if:

  • Diagnosis of mania, psychosis, or bipolar disorder
  • Impediments to TMS or MRI (i.e. metal implants in body)
  • Prior electroconvulsive therapy or vagus nerve stimulation
  • Diagnosis of Autism Spectrum Disorder.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Alberta Children's Hospital

Calgary, Alberta, T3B 6A8, Canada

Location

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Open label
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

August 25, 2020

First Posted

August 31, 2020

Study Start

November 24, 2025

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

December 31, 2027

Last Updated

November 25, 2025

Record last verified: 2025-11

Locations

CA(1)