The Fasting and Shifted Timing (FAST) of Eating Study

NCT04527952 | Completed

• 1 other identifier: Pro00089911
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to assess peoples' satisfaction with their diet based on adhering to three different meal-timing protocols for one week each: (1) Time-restricted feeding (TRF); (2) Intermittent fasting (IF); and (3) Alternate day fasting (ADF). The overall goal of this study is to determine if people would find it easy or difficult to follow these diet protocols for the purpose of weight management.

Conditions

Overweight and Obesity

Keywords

fasting

Outcome Measures

Primary Outcomes (3)

• Weight loss-week 1

  We will assess weight loss via self-report after 1 week on diet #1

  1 week

• Weight loss- week 2

  We will assess weight loss via self-report after 1 week on diet #2

  1 week

• Weight loss- week 3

  We will assess weight loss via self-report after 1 week on diet #3

  1 week

Secondary Outcomes (3)

• Energy intake-week 1

  6 weeks

• Energy intake- week 2

  6 weeks

• Energy intake- week 3

  6 weeks

Study Arms (3)

Time-restricted feeding (TRF)

EXPERIMENTAL

Participants will eat the majority of their calories in the day. More specifically participants will consume 70% of their total calories before 5 pm and the remaining 30% after 5 pm.

Behavioral: Online handouts describing how to follow each diet for 1 week each

Intermittent fasting (IF)

ACTIVE COMPARATOR

This involves eating all of one's meals within a specific time (e.g. 8 hours) frame and fasting for the remaining hours (16 hours) in a day.

Behavioral: Online handouts describing how to follow each diet for 1 week each

Alternate day fasting (ADF)

ACTIVE COMPARATOR

This involves complete fasting (i.e. no food or caloric containing beverages, only water consumption) for roughly an entire 36-hour period, followed by an ad libitum feeding day.

Behavioral: Online handouts describing how to follow each diet for 1 week each

Interventions

Online handouts describing how to follow each diet for 1 week each BEHAVIORAL

Participants will receive handouts via email about how to follow each diet

Alternate day fasting (ADF); Intermittent fasting (IF); Time-restricted feeding (TRF)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Be 18 years or older.
• Have a BMI between 25 - 49.9 kg/m2.
• Have a scale at home, or some way of weighing yourself regularly, so that you can report your body weight to the research staff.
• Be able to check emails regularly, because all of the surveys need to be completed online.

You may not qualify if:

• NOT be already practicing any of these fasting approaches.
• NOT currently diagnosed with diabetes.
• NOT taking any appetite suppressants or prescription weight loss medications.
• NOT planning on getting pregnant within the next 6 weeks.
• Do NOT currently have any eating disorders.
• Have NOT lost or gained a significant amount of weight (i.e. 10 pounds or more) within the last 6 months.

Sponsors & Collaborators

• University of South Carolina: lead

Study Sites (1)

University of South Carolina

Columbia, South Carolina, 29208, United States

Location

Related Publications (1)

• Turner-McGrievy GM, Wirth MD, Bernhart JA, Aydin H. The Fasting and Shifted Timing (FAST) of Eating Study: A pilot feasibility randomized crossover intervention assessing the acceptability of three different fasting diet approaches. Appetite. 2022 Sep 1;176:106135. doi: 10.1016/j.appet.2022.106135. Epub 2022 Jun 16.

  PMID: 35716852 DERIVED

MeSH Terms

Conditions

Overweight; Obesity; Fasting

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Feeding Behavior; Behavior

Study Officials

• Gabrielle Turner-McGrievy

  University of South Carolina

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: August 19, 2020
• First Posted: August 27, 2020
• Study Start: June 19, 2019
• Primary Completion: July 31, 2020
• Study Completion: August 1, 2020
• Last Updated: April 28, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)