NCT04523311

Brief Summary

This study aims to conduct an initial evaluation of whether a single, online, group-based session of hypnosis followed by self-hypnosis can decrease symptoms of migraine and tension-type headaches as well as improve quality of life and perceived self-efficacy over the condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 19, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 21, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

October 27, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 24, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 24, 2021

Completed
Last Updated

July 27, 2021

Status Verified

July 1, 2021

Enrollment Period

4 months

First QC Date

August 19, 2020

Last Update Submit

July 26, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change from baseline at 7-8 weeks in mean headache rating averaged over 2 weeks of headache diary entries.

    At baseline (weeks 0-1) and post-intervention (weeks 7-8), participants will complete a headache diary for two weeks. The diary comprises hourly ratings of headache intensity (during waking hours) on a 0-5 scale, with higher scores indicating greater migraine/tension-type headache symptom burden. The mean rating over two weeks is used.

    Post intervention (weeks 7-8)

Secondary Outcomes (15)

  • Change from baseline at 11-12 weeks in mean headache rating averaged over 2 weeks of headache diary entries.

    Follow-up (weeks 11-12)

  • Change from baseline at 7-8 weeks in headache frequency over 2 weeks of headache diary entries.

    Post intervention (weeks 7-8)

  • Change from baseline at 11-12 weeks in headache frequency over 2 weeks of headache diary entries.

    Follow-up (weeks 11-12)

  • Change from baseline at 7-8 weeks in mean headache duration over 2 weeks of headache diary entries.

    Post intervention (weeks 7-8)

  • Change from baseline at 11-12 weeks in mean headache duration over 2 weeks of headache diary entries.

    Follow-up (weeks 11-12)

  • +10 more secondary outcomes

Other Outcomes (3)

  • Baseline scores on the Credibility/Expectancy of Change Questionnaire will moderate the primary and secondary outcomes.

    Baseline (week 0)

  • Baseline scores on the Attitudes Towards Hypnosis scale will moderate the primary and secondary outcomes specified above.

    Baseline (week 0)

  • Week 2 scores of a bespoke measure of hypnotic suggestibility will predict the degree of change in the primary and secondary outcomes specified above [this applies to the intervention group only].

    Within the online, group-based intervention session (week 2).

Study Arms (2)

Hypnosis + usual care

EXPERIMENTAL

An online, group-based, single session hypnosis workshop followed by 2 weeks of self hypnosis. Participants will continue with whatever usual care they receive/undertake.

Behavioral: Hypnosis.Other: Usual care

Waitlist control + usual care

OTHER

The control group will receive no intervention beyond whatever usual care they receive/undertake. After the study is complete, they will be offered the option of participating in the hypnosis intervention.

Other: Usual care

Interventions

Hypnosis.BEHAVIORAL

Online, group-based, single session hypnosis workshop followed by 2 weeks of self hypnosis.

Hypnosis + usual care

Participants will be asked to continue with whatever interventions they are already receiving/employing to manage their migraine and tension-type headaches.

Hypnosis + usual careWaitlist control + usual care

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-reported diagnosis of migraine or tension-type headaches from a General Practitioner (i.e. family physician) and/or specialist physician.
  • Score above the cut-off for either migraine or tension-type headache on the Headache Screening Questionnaire.
  • Have experienced at least one headache every two weeks over the last 3 months.
  • Otherwise healthy physically and mentally.
  • Able to understand written and spoken English.
  • Have the IT equipment necessary to access Zoom videoconferencing and the Qualtrics survey system.

You may not qualify if:

  • Substantial medical or psychiatric co-morbidities including diagnoses of epilepsy, psychosis or personality disorder, and/or taking psychiatric medication.
  • A diagnosis of medication overuse headache.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Salomons Institute for Applied Psychology

Royal Tunbridge Wells, United Kingdom

Location

MeSH Terms

Conditions

Migraine DisordersTension-Type Headache

Interventions

Hypnosis

Condition Hierarchy (Ancestors)

Headache Disorders, PrimaryHeadache DisordersBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Paul Davies, MSc

    Canterbury Christ Church University

    PRINCIPAL INVESTIGATOR
  • Fergal Jones, PhD, PsychD

    Canterbury Christ Church University

    STUDY DIRECTOR
  • Robert Agnew, DClinPsych

    Private Practice

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 19, 2020

First Posted

August 21, 2020

Study Start

October 27, 2020

Primary Completion

February 24, 2021

Study Completion

February 24, 2021

Last Updated

July 27, 2021

Record last verified: 2021-07

Locations