NCT02269501

Brief Summary

The purpose of this study is to study the effect of a physical exercise program on patients suffering from migraine and co-existing tension-type headache and neck pain. The investigators hypothesized that migraine patients are ofte physically inactive because of their headache and that they will benefit from a specific exercise program.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2012

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

July 10, 2014

Completed
3 months until next milestone

First Posted

Study publicly available on registry

October 21, 2014

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2016

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 23, 2018

Completed
Last Updated

February 8, 2019

Status Verified

February 1, 2019

Enrollment Period

3.8 years

First QC Date

July 10, 2014

Last Update Submit

February 7, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in pain

    Pain intensity, pain frequency and pain duration for migraine, tension-type headache and neck pain based on four-weeks headache and neck pain diaries prior inclusion; and diaries filled out each day for three months during intervention and again four weeks prior to six months follow-up and again four weeks prior to 12 months follow-up

    At baseline and after three, six and 12 months follow-up

Secondary Outcomes (3)

  • Changes in headache and neck pain impact

    At baseline and after three, six and 12 months follow-up

  • Changes in quatitative sensory testing

    At baseline and after three and six months follow-up

  • Changes in aerobic fitness

    At baseline and after three and six months follow-up

Study Arms (2)

Exercise treatment

EXPERIMENTAL

Exercise treatment

Other: Exercise treatment

No treatment

NO INTERVENTION

No treatment

Interventions

Exercise treatment

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Migraine
  • Tension-type headache
  • Neck pain

You may not qualify if:

  • Whiplash injury or other significant neck trauma
  • Nerve root compression
  • Post traumatic headache
  • Medication overuse headache
  • Cluster headache
  • Trigeminal neuralgia
  • Pregnancy and breast feeding
  • Severe physical and psychological illnesses
  • Alcohol and or drug abuse
  • Current insurance claim owing to headache
  • Persons not able to speak or understand Danish
  • Persons deemed not to implement the program because of musculoskeletal pain or physical limitations

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Danish Headache Center, Department of Neurology

Glostrup Municipality, 2600, Denmark

Location

MeSH Terms

Conditions

Migraine DisordersTension-Type HeadacheNeck Pain

Condition Hierarchy (Ancestors)

Headache Disorders, PrimaryHeadache DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PT, MPH, PhD student

Study Record Dates

First Submitted

July 10, 2014

First Posted

October 21, 2014

Study Start

November 1, 2012

Primary Completion

September 1, 2016

Study Completion

May 23, 2018

Last Updated

February 8, 2019

Record last verified: 2019-02

Locations