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Medial Border of Laparoscopic D3 Lymphadenectomy for Right Colon Cancer
the Medial Border Along the Left Side of SMA Versus the Left Side of SMV in Laparoscopic D3 Lymphadenectomy for Right Colon Cancer, a Prospective Cohort Study
1 other identifier
observational
N/A
0 countries
N/A
Brief Summary
This study investigats the gastrointestinal functional outcomes of laparoscopic D3 lymphadenectomy for right colon cancer with the medial border along the left side of superior mesenteric artery (SMA) versus the left side of superior mesenteric vein (SMV). This is a single center, prospective cohort study with a sample size of 264 patients. The primary endpoint is the incidence of diarrhea (evaluated using the Diarrhea Assessment Scale) one month after surgery.
Trial Health
Trial Health Score
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Started Dec 2022
Typical duration for all trials
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Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 16, 2020
CompletedFirst Posted
Study publicly available on registry
August 19, 2020
CompletedStudy Start
First participant enrolled
December 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
October 31, 2025
CompletedFebruary 26, 2024
February 1, 2024
11 months
August 16, 2020
February 22, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
incidence of diarrhea
Diarrhea Assessment Scale: stool score ≥ 5
one month after surgery
Study Arms (2)
SMA group
the medial border along the left side of superior mesenteric artery (SMA)
SMV group
the medial border along the left side of superior mesenteric vein (SMV)
Interventions
to place the medial border along the left side of SMA in laparoscopic D3 lymphadenectomy for right colon cancer
to place the medial border along the left side of SMV in laparoscopic D3 lymphadenectomy for right colon cancer
Eligibility Criteria
conlon cancer located at right hemi-colon
You may qualify if:
- Age between 18 and 75 years
- American Society of Anesthesiologists (ASA) score I to III
- A biopsy proven histological diagnosis of colorectal carcinoma
- tumor located at right half of colon
- Undergoing laparoscopic right hemi-colectomy
- preoperative staging cT2-4aN0M0 or cTanyN+M0
- willing to participate and informed consent signed
You may not qualify if:
- Pregnant or lactating women
- Synchronous colorectal carcinoma
- History of colorectal cancer or other malignant tumors
- Clinical evidence of metastasis
- Preoperative staging cT1N0 or cT4bNany
- Emergency procedure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Attending surgeon of gastrointestinal surgery，Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Study Record Dates
First Submitted
August 16, 2020
First Posted
August 19, 2020
Study Start
December 1, 2022
Primary Completion
October 31, 2023
Study Completion
October 31, 2025
Last Updated
February 26, 2024
Record last verified: 2024-02