Effect of Drinking Carbohydrate-containing Fluids on Gastric Residual Volume in Elderly Patients

NCT04514380 | Completed

• 1 other identifier: B-2008/633-301
• Study Type: observational
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

In the past, some guidelines advised no oral intake for at least 8 hours before any surgery. However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting. The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited. In our institution, there are two clinical pathways for total knee arthroplasty according to the surgeons. One difference is whether carbohydrate fluids drink or not before surgery. The purpose of this study, therefore, is to assess gastric volume in fasted elderly patients using ultrasound after they drank carbohydrate fluids 2 hours before surgery and to compare with matched patients using age, body mass index, and comorbidity, who did not drink carbohydrate fluids before surgery.

Conditions

Fasting

Outcome Measures

Primary Outcomes (1)

• Gastric volume

  Gastric volume measured before induction of spinal anesthesia using ultrasound

  During the gastric volume measuring at preoperative holding area/ an average of 30 minutes

Study Arms (2)

Group C

Patients drank carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon A.

Other: Carbohydrate fluid

Group N

Patients did not drink carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon B.

Other: Non-carbohydrate fluid

Interventions

Carbohydrate fluid OTHER

400 mL carbohydrate fluid

Group C

Non-carbohydrate fluid OTHER

0 mL carbohydrate fluid

Group N

Eligibility Criteria

• Age: 65 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing total knee arthroplasty

You may qualify if:

• Patients undergoing total knee arthroplasty
• Age: 65\~85 yeas
• ASA 1\~3

You may not qualify if:

• Age \< 65 years
• ASA \>= 4
• Diabetes mellitus
• Chronic kidney disease

Sponsors & Collaborators

• Seoul National University Bundang Hospital: lead

Study Sites (1)

Seoul National Univ. Bundang Hospital

Seongnam-si, Gyeonggi-do, 463-707, South Korea

Location

Related Publications (1)

• Shin HJ, Koo BW, Lim D, Na HS. Ultrasound assessment of gastric volume in older adults after drinking carbohydrate-containing fluids: a prospective, nonrandomized, and noninferiority comparative study. Can J Anaesth. 2022 Sep;69(9):1160-1166. doi: 10.1007/s12630-022-02262-9. Epub 2022 Apr 21.

  PMID: 35449247 DERIVED

MeSH Terms

Conditions

Fasting

Condition Hierarchy (Ancestors)

Feeding Behavior; Behavior

Study Officials

• Hyo-Seok Na, MD., PhD.

  Seoul National University Bundang Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 12, 2020
• First Posted: August 14, 2020
• Study Start: September 16, 2020
• Primary Completion: March 19, 2021
• Study Completion: March 19, 2021
• Last Updated: March 22, 2021

Record last verified: 2021-03

Locations

KR (1)