Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.
INSPiRED-WP3
1 other identifier
observational
460
1 country
1
Brief Summary
Malaria, schistosomiasis and ancylostomiasis are three parasitic diseases which affect hundreds of millions of people and are an important cause of global mortality and morbidity. For the control of these poverty related parasitic diseases, and to complement chemotherapeutic strategies, accurate and accessible diagnostic procedures play a crucial role. In recent years, innovative smart mobile technologies have been applied for detection and identification of cultured parasite species, which is basically based on sample imaging and parasite morphology identification. Promising advances have been made with this technology and coupled with its small size, low cost and easy to manipulate, makes it suitable for point of care diagnostics in low resource setting. The aim of the proposed explorative study is to further validate sensitivity and specificity of each of the developed devices, using besides microscopy a range of more advanced reference tests.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2020
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 20, 2020
CompletedFirst Submitted
Initial submission to the registry
July 13, 2020
CompletedFirst Posted
Study publicly available on registry
August 7, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedAugust 7, 2020
August 1, 2020
2.8 years
July 13, 2020
August 6, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
AiDx devise is good as a conventional microscopy
Optical diagnostic devices is specific, sensitive as well as predicting value as microscopic test
3 years
Schistoscope
Optical diagnostic devices is specific, sensitive as well as predicting value as microscopic test
3 years
Hookworm and other STH devise is good as conventional. microscopic test
Optical diagnostic devices is specific, sensitive as well as predicting value as microscopic test
3 years
Eligibility Criteria
All study participants, living in Lambaréné areas and its surrounding with parasitic infection
You may qualify if:
- Infected with malaria
- Infected with Schistosomiasis
- Soil-transmitted helminths
You may not qualify if:
- No sample provided
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre de Recherches Medicales de Lambarene
Lambaréné, Moyen-Ogooué Province, BP 242, Gabon
Related Publications (1)
Meulah B, Oyibo P, Hoekstra PT, Moure PAN, Maloum MN, Laclong-Lontchi RA, Honkpehedji YJ, Bengtson M, Hokke C, Corstjens PLAM, Agbana T, Diehl JC, Adegnika AA, van Lieshout L. Validation of artificial intelligence-based digital microscopy for automated detection of Schistosoma haematobium eggs in urine in Gabon. PLoS Negl Trop Dis. 2024 Feb 23;18(2):e0011967. doi: 10.1371/journal.pntd.0011967. eCollection 2024 Feb.
PMID: 38394298DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Romuald Mba, MSc
Centre de Recherches Médicales de Lambaréné - CERMEL
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 13, 2020
First Posted
August 7, 2020
Study Start
March 20, 2020
Primary Completion
December 31, 2022
Study Completion
December 31, 2023
Last Updated
August 7, 2020
Record last verified: 2020-08