Collection of Information to Better Understand Young Onset Colorectal Cancer
Young Onset Gastrointestinal Cancer Prospective Registry
1 other identifier
observational
1,366
1 country
8
Brief Summary
The purpose of this registry study is to create a database-a collection of information-for better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this database to learn more about how young onset colorectal cancer may be similar to or different from colorectal cancer that is diagnosed later in life. Researchers will also use information from the database for current and future research on young onset colorectal cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2020
Longer than P75 for all trials
8 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 22, 2020
CompletedFirst Submitted
Initial submission to the registry
July 23, 2020
CompletedFirst Posted
Study publicly available on registry
July 28, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 22, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
July 22, 2026
February 6, 2026
February 1, 2026
6 years
July 23, 2020
February 4, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Establish a prospective database of patients with Young Onset Colorectal Cancer
from diagnosis through survivorship
1 year
Study Arms (2)
Young onset Colorectal Cancer Participants
(Stool collection on newly diagnosed patients in this cohort) Participants will include patients under the age of 50 who are diagnosed with colorectal adenocarcinoma.
Average onset Colorectal Cancer Participants
(Stool collection cohort only) 166 colorectal cancer patients 50 year-old or older will serve as controls. Stool collection cohort only.
Interventions
Participants, both cases and controls, will complete the CYOC risk factor questionnaire, preferably at the time of first visit
Eligibility Criteria
Potential research subjects will be identified through the Center for Young Onset Gastrointestinal Cancer, a member of the patient's treatment team, the principal investigator, or research team at Memorial Sloan Kettering Cancer Center (MSKCC). All study participants will be recruited from patients under the care of consenting professionals. If the investigator is a member of the treatment team, s/he will screen their patient's medical records for suitable research study participants and discuss the study and their potential for enrolling in the research study. Potential subjects contacted by their treating physician will be referred to the investigator/research staff of the study.
You may qualify if:
- Histological or cytological diagnosis of gastrointestinal cancer
- years old at time of consent
- No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)
- No history of inflammatory bowel disease (stool collection cohort only)
- No prior diagnosis of gastrointestinal cancer (stool collection cohort only)
- Histological or cytological diagnosis of colorectal adenocarcinoma
- No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)
- Age 50 or older at time of consent
- No Known hereditary CRC or other cancer predisposition syndrome
- No history of inflammatory bowel disease
- No prior diagnosis of CRC
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (8)
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center @ Commack
Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
MSK at Ralph Lauren
New York, New York, 10035, United States
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
Memorial Sloan Kettering Nassau
Rockville Centre, New York, 11553, United States
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Andrea Cercek, MD
Memorial Sloan Kettering Cancer Center
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Year
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 23, 2020
First Posted
July 28, 2020
Study Start
July 22, 2020
Primary Completion (Estimated)
July 22, 2026
Study Completion (Estimated)
July 22, 2026
Last Updated
February 6, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will share
Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.