Use of PRF in Treatment of Dry Socket.

NCT04476121 | Unknown

• 1 other identifier: 0002
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to evaluate the influence of PRF application in case of alveolar osteitis.

Conditions

Alveolar Osteitis

Keywords

dry socket; PRF

Outcome Measures

Primary Outcomes (2)

• Intensity of pain vs. PRF and Nipas application

  In order to evaluate the relationship between intensity of pain after application of PRF and Nipas, Numeric Rating Scale pain scale is used. NRS is a horizontal line with an eleven point numeric range. It is labeled from zero to ten, with zero being an example of someone with no pain and ten being the worst pain possible. The higher score means worse outcome in case of present study.

  24 hours

• Influence of treatment on bacteria levels in wounds

  The second part of the study was dedicated to analyzing the number of bacteria in tooth extraction wounds.

  24 hours

Study Arms (2)

PRF application

EXPERIMENTAL

Patients with alveolar osteitis in which PRF application was performed.

Procedure: PRF application

Aspirin application

ACTIVE COMPARATOR

Patients with alveolar osteitis in which Nipas was used.

Drug: Nipas application

Interventions

PRF application PROCEDURE

PRF application into post-operative wound.

PRF application

Nipas application DRUG

Nipas application into post-operative wound.

Also known as: Aspirin paste

Aspirin application

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• no known medical history of abnormal platelet counts,
• patients with symmetric teeth qualified for extraction,

You may not qualify if:

• patients treated previously for existing dry socket,
• patients allergic to acetylsalicylic acid ,
• systemic diseases,
• pregnancy,
• lactation,
• drugs known to affect the number or function of platelets,
• abnormal platelet counts,

Sponsors & Collaborators

• Medical University of Lodz: lead

Study Sites (1)

Department of Oral Surgery

Lodz, 92-213, Poland

Location

MeSH Terms

Conditions

Dry Socket

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases

Study Officials

• Anna Janas-Naze, Prof.

  Medical University of Lodz

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: The first medicine was applied, if dry socket was diagnosed following a tooth extraction. In case of subsequent extraction of homonymous tooth in the same patient and reoccurrence of dry socket, patients were treated with PRF application.

Study Record Dates

• First Submitted: July 15, 2020
• First Posted: July 17, 2020
• Study Start: January 1, 2019
• Primary Completion: July 1, 2021
• Study Completion: July 1, 2021
• Last Updated: April 26, 2021

Record last verified: 2020-06

Locations

PL (1)