NCT04466436

Brief Summary

Surgery has many immunomodulatory properties of which the mechanism is not clearly understood.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

July 8, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 10, 2020

Completed
29 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 8, 2020

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 10, 2020

Completed
Last Updated

July 16, 2020

Status Verified

July 1, 2020

Enrollment Period

1 month

First QC Date

July 8, 2020

Last Update Submit

July 14, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • tryptophan metabolites in serum

    72 hours

Study Arms (2)

CABG group

Other: tryptophan

spine group

Other: tryptophan

Interventions

measurement of tryptophan in serum

CABG groupspine group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

adults undergoing elective surgery

You may qualify if:

  • elective surgery

You may not qualify if:

  • emergency surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assiut university

Asyut, 71111, Egypt

RECRUITING

MeSH Terms

Interventions

Tryptophan

Intervention Hierarchy (Ancestors)

Amino Acids, AromaticAmino Acids, CyclicAmino AcidsAmino Acids, Peptides, and ProteinsAmino Acids, Essential

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of anaesthesia

Study Record Dates

First Submitted

July 8, 2020

First Posted

July 10, 2020

Study Start

July 8, 2020

Primary Completion

August 8, 2020

Study Completion

August 10, 2020

Last Updated

July 16, 2020

Record last verified: 2020-07

Locations