NCT04465838

Brief Summary

This research is a multicenter,observational study under real world settings in patients diagnosed as psoriasis by dermatologist in the clinic. As patient's choice of medication should be fully respected, all the patients can choose the treatments they prefer, like phototherapy, traditional systemic therapy or biologics. And the study was conducted to compare the effectiveness among different choices of medication in Chinese psoriasis patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
50mo left

Started Jul 2020

Longer than P75 for all trials

Geographic Reach
1 country

29 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress58%
Jul 2020Jul 2030

First Submitted

Initial submission to the registry

June 26, 2020

Completed
12 days until next milestone

Study Start

First participant enrolled

July 8, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 10, 2020

Completed
10 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 13, 2030

Expected
17 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 30, 2030

Last Updated

January 5, 2024

Status Verified

January 1, 2024

Enrollment Period

10 years

First QC Date

June 26, 2020

Last Update Submit

January 4, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • The percentage of patients who achieved a PASI reduction of 100% (PASI 100)

    Psoriasis Area and Severity Index includes scores of erythema, infiltration and desquamation, weighted by area of involvement in each regions (head and neck, upper extremities, trunk, lower extremities), with higher PASI scores indicating worse condition. The percentage of patients who achieved a PASI reduction of 100% (PASI 100) will be measured.

    6 months

Secondary Outcomes (9)

  • The percentage of patients who achieved a PASI reduction of 100% (PASI 100)

    6 months and 12 months

  • The percentage of patients who achieved a PASI reduction of 75% (PASI 75)

    6 months and 12 months

  • The percentage of patients who achieved a PASI reduction of 50% (PASI 50)

    6 months and 12 months

  • static Physician Global Assessment (sPGA) = 0

    6 months and 12 months

  • static Investigator Global Assessment (sIGA) = 0

    6 months and 12 months

  • +4 more secondary outcomes

Study Arms (1)

Psoriasis

This is a non-interventional study (NIS). All the patients diagnosed as psoriasis by the dermatologists in the clinic are included in this study no matter what kind of treatment they adopt.

Other: NIS

Interventions

NISOTHER

This is a non-interventional study (NIS).

Psoriasis

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All the patients diagnosed as psoriasis by dermatologist in clinic were under treatment or willing to be treated.

You may qualify if:

  • all the patients diagnosed as psoriasis by dermatologist in clinic.

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (29)

Second Affiliated Hospital, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, 310000, China

RECRUITING

Beijing Children's Hospital Affiliated to Capital Medical University

Beijing, China

RECRUITING

the First Affiliated Hospital of Chongqing Medical University

Chongqing, China

RECRUITING

the First Affiliated Hospital of Fujian Medical University

Fujian, China

RECRUITING

General Hospital of Lanzhou Military Region

Gansu, China

RECRUITING

Sun Yat-sen Memorial Hospital

Guangdong, China

RECRUITING

The Peoples' Hospital of Guangxi Zhuang Autonomous Region

Guangxi, China

RECRUITING

the Affiliated Hospital of Guizhou Medical University

Guizhou, China

RECRUITING

The Fifth People's Hospital of Hainan Province

Hainan, China

RECRUITING

the First Hospital of Hebei Medical University

Hebei, China

RECRUITING

the Second Affiliated Hospital of Harbin Medical Unviersity

Heilongjiang, China

RECRUITING

Henan Provincial Peoples' Hospital

Henan, China

RECRUITING

the Affiliated Hospital of Inner Mongolia Medical University

Hohhot, China

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Hubei, China

RECRUITING

Xiangya Hospital, Central South University

Hunan, China

RECRUITING

the Second Affiliated Hospital of Nanchang University

Jiangxi, China

RECRUITING

Yanbian University Hospital

Jilin, China

RECRUITING

Institute of Dermatology, Chinese Academy of Medical Sciences

Nanjing, China

RECRUITING

Xining First Hospital

Qinghai, China

RECRUITING

Shandong Provincial Hospital for Skin Diseases

Shandong, China

RECRUITING

Shanghai Dermatology Hospital

Shanghai, China

RECRUITING

Taiyuan Central Hospital

Shanxi, China

ENROLLING BY INVITATION

the Second Affiliated Hospital of Xi'an Jiaotong University

Shanxi, China

RECRUITING

the First hospital of China Medical University

Shenyang, China

RECRUITING

Sichuan Provincial People's Hospital

Sichuan, China

RECRUITING

Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

Tianjin, China

RECRUITING

First Affiliated Hospital, School of Medicine, Shihezi University

Xinjiang, China

RECRUITING

General Hospital of Ningxia Medical University

Yinchuan, China

RECRUITING

the Second Affiliated Hospital of Kunming Medical University

Yunnan, China

RECRUITING

MeSH Terms

Conditions

Psoriasis

Condition Hierarchy (Ancestors)

Skin Diseases, PapulosquamousSkin DiseasesSkin and Connective Tissue Diseases

Central Study Contacts

Xiao-yong Man, MD

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Head of Dermatology

Study Record Dates

First Submitted

June 26, 2020

First Posted

July 10, 2020

Study Start

July 8, 2020

Primary Completion (Estimated)

July 13, 2030

Study Completion (Estimated)

July 30, 2030

Last Updated

January 5, 2024

Record last verified: 2024-01

Locations