NCT04452045

Brief Summary

This proposal will acquire preliminary data on the feasibility and effectiveness of an innovative and scalable strategy for improving access to effective sleep health care for preschool-aged children with Autism Spectrum Disorder (ASD). The investigators will develop and test an on-line delivery adaptation of the existing behavioral sleep interventions for preschool aged children.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 25, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 30, 2020

Completed
2 months until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2021

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
3.9 years until next milestone

Results Posted

Study results publicly available

December 2, 2025

Completed
Last Updated

December 2, 2025

Status Verified

November 1, 2025

Enrollment Period

1.3 years

First QC Date

June 25, 2020

Results QC Date

April 24, 2023

Last Update Submit

November 18, 2025

Conditions

Keywords

sleepautism

Outcome Measures

Primary Outcomes (1)

  • Change in Children's Sleep Habits Questionnaire (CSHQ)

    Validated questionnaire; total score range between 33 and 99, with higher numbers representing more sleep problems

    baseline to end of treatment (average exposure 1 month)

Secondary Outcomes (1)

  • Change in Pittsburgh Sleep Quality Index (PSQI)

    baseline to end of treatment (average exposure 1 month)

Study Arms (2)

SweetDreams

EXPERIMENTAL

Access to a mobile and computer accessible adaptation of existing evidence based sleep interventions.

Device: SweetDreams

Waitlist Control

NO INTERVENTION

Wait list condition with future access to a mobile and computer accessible adaptation of existing evidence based sleep interventions.

Interventions

SweetDreams is a mHealth adaptation of existing evidence-based sleep interventions. It is a user friendly and developmentally appropriate modularized 4-week web-based intervention available on computer, tablet or mobile phones.

SweetDreams

Eligibility Criteria

Age12 Months - 60 Months
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • have poor sleep health
  • have a diagnosis of ASD

You may not qualify if:

  • any regular sleep medication use (this does not include occasional over the counter sleep aid)
  • known sleep apnea
  • unstable major medical conditions (e.g. severe asthma, diabetes).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94143, United States

Location

MeSH Terms

Conditions

Autism Spectrum DisorderSleep Initiation and Maintenance DisordersAutistic Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental DisordersSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Results Point of Contact

Title
Lauren Asarnow
Organization
University of California, San Francisco

Study Officials

  • Lauren Asarnow, PhD

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 25, 2020

First Posted

June 30, 2020

Study Start

September 1, 2020

Primary Completion

December 30, 2021

Study Completion

December 31, 2021

Last Updated

December 2, 2025

Results First Posted

December 2, 2025

Record last verified: 2025-11

Data Sharing

IPD Sharing
Will not share

Locations