Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma
ACBC
1 other identifier
observational
1,000
1 country
1
Brief Summary
P) patients with acute obstructive colon cancer I) resection or bridge to surgery with stent or stoma C) emergency procedure O ) morbidity and mortality within 30 days, 90 day mortality and 3 \& 5 years overall survival
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2020
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 14, 2020
CompletedFirst Posted
Study publicly available on registry
June 30, 2020
CompletedStudy Start
First participant enrolled
September 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2029
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2031
April 23, 2026
April 1, 2026
9.3 years
June 14, 2020
April 22, 2026
Conditions
Outcome Measures
Primary Outcomes (5)
Number of patients with 30-day severe morbidity
Clavien-Dindo \>3 within 30 days postop
30 days
Overall survival after 3 years
survival unspecified
3 years
Number of patients with 30 day mortality
death within 30 days
30 days
Overall survival after 5 years
survival unspecified
5 years
Number of patients with 90 day mortality
death within 90 days
90 days
Secondary Outcomes (16)
Number of patients with locally radical resections
90 days
Number of examined mesenteric lymph nodes
90 days
Proportion of patients receiving neoadjuvant or adjuvant treatment
1 year
Proportion of patients with stomas after 3 years
3 years
Recurrence rate after 3 after years
3 years
- +11 more secondary outcomes
Study Arms (2)
resection
Patients who present with obstruction due to colon cancer with a need for urgent intervention who are treated with acute resection.
bridge to sugery
Patients who present with obstruction due to colon cancer with a need for urgent intervention who are treated with bridge to surgery i.e. either stent or stoma and resection later on.
Interventions
The study is an observational study and patients will not be randomized. Resection is defined as upfront surgical resection, Bridge to Surgery as a two stage procedure.
Eligibility Criteria
Prospective observational cohort study.
You may qualify if:
- Age \>18 years
- Symptomatic large bowel obstruction requiring acute intervention
- CT-verified colon obstruction due to colon cancer independent of presence of metastases
- Informed consent
You may not qualify if:
- Colonic perforation or bleeding
- Colonic obstruction of other origin than colon cancer
- Palliative situation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Skane University Hospitallead
- Göteborg Universitycollaborator
Study Sites (1)
Göteborg University
Gothenburg, Sweden
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Pamela Buchwald, PhD MD
Skåne University Hospital, Lund University
- STUDY CHAIR
Tobias Axmarker, MD
Skåne University Hospital, Lund University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- consultant colorectal surgeon, associate professor
Study Record Dates
First Submitted
June 14, 2020
First Posted
June 30, 2020
Study Start
September 1, 2020
Primary Completion (Estimated)
December 31, 2029
Study Completion (Estimated)
December 31, 2031
Last Updated
April 23, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL