NCT04448535

Brief Summary

The purpose of this study is to understand the effect of Ginkgo Biloba oral supplements on retinal and choroidal ocular tissue.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at P25-P50 for not_applicable healthy

Timeline
Completed

Started Jan 2021

Typical duration for not_applicable healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 24, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 26, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

January 1, 2021

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 3, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 3, 2022

Completed
Last Updated

October 24, 2022

Status Verified

October 1, 2022

Enrollment Period

1.6 years

First QC Date

June 24, 2020

Last Update Submit

October 20, 2022

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

  • ocular blood flow

    ocular blood flow measured with doppler ultrasound

    4 weeks

Study Arms (1)

Gingko Biloba

EXPERIMENTAL

oral intake of gingko biloba for 4 weeks

Dietary Supplement: Gingko Biloba

Interventions

Gingko BilobaDIETARY_SUPPLEMENT

oral intake of Gingko Biloba, 240mg/day for 4 weeks

Gingko Biloba

Eligibility Criteria

Age20 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Aged between 20 - 55 years, inclusive
  • Good general and ocular health
  • Corrected visual acuity of 20/40 or better
  • No gingko biloba supplementation within the last 3 months

You may not qualify if:

  • All significant ocular and any systemic disorders considered likely to affect the systemic or ocular vasculature
  • History of ocular surgery, including refractive surgery
  • Use of ocular medications
  • Conditions where ginkgo supplementation is contraindicated
  • Any eye or systemic disease that affect vision or refractive error
  • Current smokers
  • Subjects who are pregnant, breastfeeding, or planning conception

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SUNY College of Optometry

New York, New York, 10036, United States

Location

MeSH Terms

Interventions

Ginkgo Extract

Intervention Hierarchy (Ancestors)

Plant ExtractsPlant PreparationsBiological ProductsComplex Mixtures

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Clinical Professor

Study Record Dates

First Submitted

June 24, 2020

First Posted

June 26, 2020

Study Start

January 1, 2021

Primary Completion

August 3, 2022

Study Completion

August 3, 2022

Last Updated

October 24, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations

US(1)