Brain Health in the Time of COVID-19

NCT04438967 | Unknown

• 1 other identifier: MIRO_001_2020
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

This is a nationwide research program to study the neurological effects of COVID-19. It is open to the public. Healthy individuals and individuals who are or have been infected with COVID-19 are encouraged to join the effort. The study can be done at home with internet access and an iPad or iPhone. Participation takes about one hour. To learn more, go to https://www.mirohealth.com/consent/

Conditions

Brain Health

Keywords

COVID-19; neurocognitive; stroke; nervous system

Outcome Measures

Primary Outcomes (2)

• Test the hypothesis that COVID-19 infection will lead to increased risk of neurological impairment

  Each participant's Risk Score of mild cognitive impairment will be calculated using machine learning methods on a percent range of 0-100%. Miro Mobile Assessments will measure each individual's functional performance in neurocognitive, neurobehavioral, motor, and emotional domains. Miro Mobile is a clinically-validated iPad application in use by Johns Hopkins and other research centers. Miro Questionnaires will gather each individual's demographic data. To learn more, go to https://www.mirohealth.com/consent/ Miro Functional Assessments evaluate: Attention Executive function Learning and Memory Motor function Processing speed Speech and language Visuospatial function

  ~1 year

• Determine cognitive and behavioral functional patterns that predict susceptibility to neurological impairment due to COVID-19

  Miro Questionnaires will gather each individual's demographic and medical history data. Miro Mobile Assessments will measure each individual's CNS functional performance. From this data, Miro will test the hypothesis that health indicators exist that can predict the likelihood of a COVID-19 infection leading to neurological impairment. Miro Functional Assessments evaluate: Attention Executive function Learning and Memory Motor function Processing speed Speech and language Visuospatial function

  ~1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study population is open to anyone over the age of 18 who can consent for themself.

You may qualify if:

• years of age or older
• Access to an iPad bought in 2013 or later
• Access to stable Wi-Fi
• Access to iTunes

You may not qualify if:

• Below age 18
• Preexisting neurological, psychiatric, or developmental disorder

Sponsors & Collaborators

• Miro Health: lead
• Johns Hopkins University: collaborator
• University of Pittsburgh: collaborator

Study Sites (1)

Miro Health

San Francisco, California, 94107, United States

RECRUITING

Related Links

• Asadi-Pooya \& Simani 2020; Leonardi et al., 2020, Wu et al., 2020

MeSH Terms

Conditions

COVID-19; Stroke; Neurologic Manifestations

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Natasha Belfor, PhD

  Miro Health

  PRINCIPAL INVESTIGATOR

• Leah Rubin, PhD

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Natasha Belfor, PhD

CONTACT

415-655-3839; research@mirohealth.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 15, 2020
• First Posted: June 19, 2020
• Study Start: June 16, 2020
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: January 6, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will share

Locations

US (1)