The Effects of Functional Power Training on Frail and Pre-frail Community - Dwelling Older Adults in Singapore

NCT04438876 | Completed

• 1 other identifier: GERI1618
• Study Type: interventional
• Target: 61
• Locations: 1 country
• Sites: 1

Brief Summary

To investigate the efficacy of a 12-week Functional Power Training (FPT) program in pre-frail and frail community-dwelling older adults in Singapore for the management of physical frailty. The proposed study will provide information on the benefits of FPT on physical performances of older adults and help to shape future exercise recommendations to slow or reverse the onset and severity of physical frailty.

Conditions

Frailty; Muscle Weakness

Outcome Measures

Primary Outcomes (5)

• Change of Frail status at 12 and 24 weeks

  Cardiovascular Health Study (CHS) Frailty status which characterizes frailty based on five components: unintentional weight loss, weakness, slowness, exhaustion and low physical activity. 1 point for each category. Robust: 0 point, Pre-Frail: 1-2 points , Frail: 3-5 points.

  baseline, 12 weeks, 24 weeks

• Change of hand grip strength at 12 and 24 weeks

  Hand grip strength (kg)

  baseline, 12 weeks, 24 weeks

• Change of knee extensor strength at 12 and 24 weeks

  Knee extensor strength (kg)

  baseline, 12 weeks, 24 weeks

• Change of Timed up and go (TUG) at 12 and 24 weeks

  Timed up and go (TUG) (seconds)

  baseline, 12 weeks, 24 weeks

• Change of SPPB at 12 and 24 weeks

  Short Physical Performance Battery (SPPB) consist of: 1. Balance test 2. Gait speed 3. Chair stand test

  baseline, 12 weeks, 24 weeks

Secondary Outcomes (1)

• Exercise adherence

  baseline, 12 weeks, 24 weeks

Study Arms (2)

Function power training

EXPERIMENTAL

12-week structured FPT program, conducted by a certified trainer from a community service provider. Sessions were held twice weekly at the respective community senior activity centers, each lasting 60 minutes in duration.

Other: Functional Power Training

Usual care

ACTIVE COMPARATOR

Participants either continued the usual exercise program provided by their respective community senior activity centers or their personal exercise routine.

Other: Usual care

Interventions

Functional Power Training OTHER

The exercise intervention encompassed high-velocity movement, balance, and mobility exercises with the use of body weight and resistance bands as resistance. Participants were instructed to move rapidly during the concentric phase and slowly during the eccentric phase when performing the dynamic exercises.

Function power training

Usual care OTHER

Participants either continued the usual exercise program provided by their respective community senior activity centers or their personal exercise routine.

Usual care

Eligibility Criteria

• Age: 55 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• aged 55 years and above
• low muscle strength - handgrip strength less than 26kg for men and 18kg for women
• ambulate without human assistance
• able to understand basic instructions

You may not qualify if:

• currently enrolled in another study
• acute musculoskeletal injury
• unable to participate in the full duration of the study
• unwilling to participate if not assigned to the intervention group
• deemed not suitable to participate in exercise by a medical doctor

Sponsors & Collaborators

• Geriatric Education and Research Institute: lead

Study Sites (1)

Geriatric Education & Research Institute

Singapore, Singapore

Location

Related Publications (1)

• Tou NX, Wee SL, Seah WT, Ng DHM, Pang BWJ, Lau LK, Ng TP. Effectiveness of Community-Delivered Functional Power Training Program for Frail and Pre-frail Community-Dwelling Older Adults: a Randomized Controlled Study. Prev Sci. 2021 Nov;22(8):1048-1059. doi: 10.1007/s11121-021-01221-y. Epub 2021 Mar 19.

  PMID: 33742266 DERIVED

MeSH Terms

Conditions

Frailty; Muscle Weakness

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms

Study Officials

• Shiou-Liang Wee, PhD

  Geriatric Education & Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 15, 2020
• First Posted: June 19, 2020
• Study Start: March 14, 2019
• Primary Completion: December 31, 2020
• Study Completion: December 31, 2020
• Last Updated: February 9, 2021

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share

Locations

SG (1)