Study Stopped
Owing to the impact of COVID-19, the study had to be withdrawn.
Westlake Gut Microbiome Study
Multi-Omic Microbiome Study: Characterization of the Human Microbiota Among Chinese Population to Understant How the Microbiome Impacts Human Health.
1 other identifier
observational
N/A
1 country
1
Brief Summary
The Westlake Gut Microbiome study is a prospective cohort study. This project aims to characterize the gut microbiome among Chinese populations from different regions of China, and explore the relationships between gut microbiota and human health. Human fecal samples will be collected from the participants and muli-omics detection and analysis will be performed.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Sep 2021
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 14, 2020
CompletedFirst Posted
Study publicly available on registry
June 17, 2020
CompletedStudy Start
First participant enrolled
September 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 30, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2028
ExpectedJune 13, 2025
May 1, 2025
3.8 years
June 14, 2020
June 10, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Gut microbiota
Fecal microbiome will be analyzed by 16S rRNA gene sequencing and metagenome sequencing.
36 months
Metabolomics of serum and gut microbiome
Metabolomics of serum and gut microbiome will be analyzed by liquid chromatograph-mass spectrometer (LC/MS)
36 months
Proteomic profiling of serum
Proteomic characterization of serum will be analyzed by liquid chromatograph-mass spectrometer (LC/MS)
36 months
Secondary Outcomes (2)
Body composition
36 months
Biochemical examination of blood samples
36 months
Eligibility Criteria
All the participants should be Chinese residents, regardless of the ethics.
You may qualify if:
- Participants or her/his legal guardian are able to report the antibiotics use during the past 3 months; Participants or her/his legal guardian are able to understand and respond to the online questionairs; Participants or her/his legal guardian are able and willing to collect the biological samples as instructed; Participants or her/his legal guardian are able and willing to provide written informed consent; -
You may not qualify if:
- Those with serious fundamental diseases or infectious diseases; and those with other conditions that not suitable to participate in this study, as considered by the investigators.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Westlake University
Hangzhou, Zhejiang, 310024, China
Biospecimen
venous blood, saliva, urine and feces.
Study Officials
- PRINCIPAL INVESTIGATOR
Ju-Sheng Zheng, PhD
Westlake University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 14, 2020
First Posted
June 17, 2020
Study Start
September 1, 2021
Primary Completion
June 30, 2025
Study Completion (Estimated)
June 30, 2028
Last Updated
June 13, 2025
Record last verified: 2025-05