Effect of Anaesthesia on Basic Aminoacids
Effect of Anaesthesia and Surgery on Plasma Levels of Nitric Oxide and Basic Aminoacids
1 other identifier
observational
58
1 country
1
Brief Summary
Basic amino acids are acids that contains amino groups more than carboxylic groups. At least five basic amino acids namely; Arginine, citrulline, ornithine, lysine and hydroxylysine metabolize in our body. Loss of body protein represents a typical feature of the catabolic response to surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 11, 2020
CompletedStudy Start
First participant enrolled
June 11, 2020
CompletedFirst Posted
Study publicly available on registry
June 16, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 2, 2020
CompletedJuly 14, 2020
July 1, 2020
6 months
June 11, 2020
July 11, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
basic aminoacids and NO levels
72 hours
Study Arms (2)
coronary artery bypass
thoracic surgery
Interventions
Eligibility Criteria
patients undergoing cardiopulmonary bypass and thoracotomy for lung resection secondary to lung carcinoma, three samples will be taken to evaluate the levels of basic amino acids and NO levels
You may qualify if:
- elective surgery
- ASA II,III
You may not qualify if:
- Emergency surgery
- Associated renal or liver disease
- Chronic disease as D.M
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut university
Asyut, 71111, Egypt
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer of anaesthesia
Study Record Dates
First Submitted
June 11, 2020
First Posted
June 16, 2020
Study Start
June 11, 2020
Primary Completion
December 1, 2020
Study Completion
December 2, 2020
Last Updated
July 14, 2020
Record last verified: 2020-07