Predictors of Postoperative Atrial Fibrillation After CABG

NCT05888168 | Unknown

• 1 other identifier: 2023065X
• Study Type: observational
• Target: 15,000
• Locations: 1 country
• Sites: 1

Brief Summary

This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Conditions

Coronary Artery Disease; Atrial Fibrillation New Onset

Keywords

coronary artery bypass grafting; postoperative atrial fibrillation

Outcome Measures

Primary Outcomes (1)

• Incidence of POAF

  This will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG.

  During hospital stay, up to 30 days

Secondary Outcomes (4)

• Hospital length of stay

  During hospital stay, up to 30 days

• ICU admission time

  During hospital stay, up to 30 days

• Number of participants with Stroke

  During hospital stay, up to 30 days

• Mortality

  During hospital stay, up to 30 days

Study Arms (2)

POAF

This group will consist of patients who have developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

Procedure: CABG

Non-POAF

This group will consist of patients who have not developed postoperative atrillary fibrillation (POAF) after undergoing coronary artery bypass grafting (CABG).

Procedure: CABG

Interventions

CABG PROCEDURE

All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Non-POAF; POAF

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The participants in this study are adult patients (18 years and older) who have undergone Coronary Artery Bypass Grafting (CABG). These individuals come from diverse demographic backgrounds and have a history of severe coronary heart disease, the condition that necessitated the CABG surgery.

You may qualify if:

• Adults aged 18 years or older.
• Patients who underwent CABG.

You may not qualify if:

• Patients with a history of preoperative atrial fibrillation or other significant arrhythmias.
• Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG.
• Patients who cannot provide informed consent or lack adequate follow-up information.

Sponsors & Collaborators

• Kun Hua: lead

Study Sites (1)

Beijing Anzhen Hospital

Beijing, China

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Kun Hua, MD

  Beijing Anzhen Hospital

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Deputy Chief Surgeon

Study Record Dates

• First Submitted: May 21, 2023
• First Posted: June 5, 2023
• Study Start: January 1, 2018
• Primary Completion: December 15, 2023
• Study Completion: May 1, 2024
• Last Updated: June 5, 2023

Record last verified: 2023-06

Locations

CN (1)