NCT04431336

Brief Summary

Aortic dissection or aneurysm is unusual in young patients, and frequently associated with unusual presentations. However studies about this area is scarce. Besides, the treatment option is not clare. The prognosis of this cohort is also unclear. The goal of this study was to better understand the characters, treatment option and prognosis of young patient with aortic dissection or aneurysm.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 5, 2020

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

June 8, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

June 16, 2020

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

June 16, 2020

Status Verified

June 1, 2020

Enrollment Period

1.5 years

First QC Date

June 8, 2020

Last Update Submit

June 11, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Clinical features of young aortic dissection and aneurysm patients

    Collecting clinical data, such as basic information, blood biochemical information and imaging informatio to describe the characteristics of young people.

    before December 2021

Study Arms (1)

younger aortic dissection or aneurysm patients

this is an observation cohort study about younger aortic dissection or aneurysm patients without intervention.

Behavioral: movement

Interventions

movementBEHAVIORAL

movement

younger aortic dissection or aneurysm patients

Eligibility Criteria

Age1 Year - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

young patients aged less than 50 years old and had aortic dissection or aneurysm

You may qualify if:

  • young patients with aortic dissection or aneurysm

You may not qualify if:

  • Aortic dissection or aneurysm due to traumatic

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Januzzi JL, Isselbacher EM, Fattori R, Cooper JV, Smith DE, Fang J, Eagle KA, Mehta RH, Nienaber CA, Pape LA; International Registry of Aortic Dissection (IRAD). Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD). J Am Coll Cardiol. 2004 Feb 18;43(4):665-9. doi: 10.1016/j.jacc.2003.08.054.

    PMID: 14975480BACKGROUND

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

To explore pathogenic genes 5m peripheral blood was extracted for whole genome sequencing.

MeSH Terms

Conditions

Aortic Dissection

Interventions

Movement

Condition Hierarchy (Ancestors)

Dissection, Blood VesselAneurysmVascular DiseasesCardiovascular DiseasesAcute Aortic SyndromeAortic Diseases

Intervention Hierarchy (Ancestors)

Physiological PhenomenaMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Zaiping MD Jing, Professor

    Vascular surgery, Changhai Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Zaiping MD Jing, professor

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
NETWORK
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 8, 2020

First Posted

June 16, 2020

Study Start

June 5, 2020

Primary Completion

November 30, 2021

Study Completion

December 31, 2021

Last Updated

June 16, 2020

Record last verified: 2020-06