Does Delaying Curative Surgery for Colorectal Cancer Influence Long-term Disease Free Survival.
1 other identifier
observational
602
0 countries
N/A
Brief Summary
This work is an original clinical research article describing the relationship between wait list tome for colorectal cancer patients and long-term survival. These findings are particularly relevant for management of surgical wait lists during crisis such as the Covid-19 pandemic. The lack of a relationship between wait list time and disease free survival and tendency for improved survival in the 4-6 week imply some colorectal cancer operations can be safely delayed during times of limited resources.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2012
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2020
CompletedFirst Submitted
Initial submission to the registry
June 10, 2020
CompletedFirst Posted
Study publicly available on registry
June 12, 2020
CompletedJune 16, 2020
June 1, 2020
6 years
June 10, 2020
June 12, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Disease-free overall survival
5 years
Study Arms (4)
Wait list time 0-2 weeks
Wait list time 0-2 weeks
Wait list time 2-4 weeks
Wait list time 2-4 weeks
Wait list time 4-6 weeks
Wait list time 4-6 weeks
Wait list time > 6 weeks
Wait list time \> 6 weeks
Interventions
Eligibility Criteria
Patients who had American Joint Committee on Cancer (AJCC) stage I through III confirmed adenocarcinomas were selected, with "colon" or "upper rectum" as their primary site of malignancy according to International Classification of Diseases for Oncology, Third Edition topography code.
You may qualify if:
- American Joint Committee on Cancer (AJCC) stage I through III confirmed adenocarcinomas
- With "colon" or "upper rectum" as their primary site of malignancy according to International Classification of Diseases for Oncology, Third Edition topography code.
You may not qualify if:
- Emergency surgery,
- More than one primary site,
- Synchronous metastasis or peritoneal carcinomatosis at the time of surgery
- If they received neoadjuvant chemoradiotherapy
- If they had a local transanal excision.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Professor
Study Record Dates
First Submitted
June 10, 2020
First Posted
June 12, 2020
Study Start
January 1, 2012
Primary Completion
December 31, 2017
Study Completion
April 1, 2020
Last Updated
June 16, 2020
Record last verified: 2020-06