NCT04430049

Brief Summary

To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021. This restrictive visit policy could result in an increase in symptoms of anxiety, depression or post-traumatic stress disorder for relatives of ICU patients. The aim of this study is to compare symptoms of anxiety, depression or post-traumatic stress for relatives of ICU patients during Covid period with those during no Covid period (2020 and 2021) with those no Covid period (2022)

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
811

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2020

Typical duration for all trials

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 10, 2020

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 12, 2020

Completed
10 days until next milestone

Study Start

First participant enrolled

June 22, 2020

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 9, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 9, 2022

Completed
Last Updated

February 8, 2023

Status Verified

June 1, 2020

Enrollment Period

2.4 years

First QC Date

June 10, 2020

Last Update Submit

February 6, 2023

Conditions

Keywords

Covid-19FamilyAnxietyDepressionPost-traumatic stress disorderIntensive Care UnitVisitation

Outcome Measures

Primary Outcomes (2)

  • Anxiety

    Anxiety for relative of ICU patient will be measured by the Hospital Anxiety and depression scale (HADS) assessed between 3 and 6 months after the ICU discharge of patient. HADS ranges from 0 to 42; higher scores indicate worse symptoms.

    Between 3 and 6 months

  • Depression

    Anxiety for relative of ICU patient will be measured by the Hospital Anxiety and depression scale (HADS) assessed between 3 and 6 months after the ICU discharge of patient. HADS ranges from 0 to 42; higher scores indicate worse symptoms.

    Between 3 and 6 months

Secondary Outcomes (1)

  • post-traumatic stress disorder

    between 3 and 6 months

Study Arms (3)

no visitation group

relatives cannot visit ICU patient during Covid pandemic period in France

Procedure: Covid ICU containment measures

restrictive visitation group

relatives have restriction to visit ICU patient during Covid pandemic period in France

Procedure: Covid ICU containment measures

open visitation group

relatives can visit ICU patient during no Covid period in France

Procedure: Covid ICU containment measures

Interventions

The french containment measures during Covid-19 pandemic result in a restrictive visitation for relatives in ICU

no visitation groupopen visitation grouprestrictive visitation group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Relative of patient who was admitted in ICU and treated with mechanical ventilation or non-invasive ventilation or high flow oxygen or amine administration during 24hours at least.

You may qualify if:

  • Relative of patient who was admitted in ICU and treated with invasive mechanical ventilation administration during 24hours at least.

You may not qualify if:

  • Relative who declines the enrollment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

University hospital, Clermont-Ferrand

Clermont-Ferrand, Auvergne, 63000, France

Location

CH Aurillac

Aurillac, 15000, France

Location

CH Cannes

Cannes, 06150, France

Location

Centre Jean Perrin

Clermont-Ferrand, 63000, France

Location

CH Grenoble

Grenoble, 38000, France

Location

CH Le Puy-en-Velay

Le Puy-en-Velay, 43000, France

Location

University hopistal, Lyon

Lyon, 69000, France

Location

CH Moulins

Moulins, 03000, France

Location

CH Périgueux

Périgueux, 24000, France

Location

CH Rodez

Rodez, 12000, France

Location

CH Vichy

Vichy, 03200, France

Location

MeSH Terms

Conditions

COVID-19Critical IllnessAnxiety DisordersDepressionStress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsMental DisordersBehavioral SymptomsBehaviorStress Disorders, TraumaticTrauma and Stressor Related Disorders

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 10, 2020

First Posted

June 12, 2020

Study Start

June 22, 2020

Primary Completion

November 9, 2022

Study Completion

November 9, 2022

Last Updated

February 8, 2023

Record last verified: 2020-06

Locations